Location · Maryland
Clinical trials recruiting in Maryland
891 recruiting studies have at least one site in Maryland; 511 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Maryland.
891 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
Evaluating the Dose, Safety, Tolerability, and Immunogenicity of Mosaic Hexavalent Influenza Vaccine VRCFLUMOS0116-00-VP (FluMos-v2) With and Without ALFQ Adjuvant in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 50–100
- RecruitingHealthy volunteersPhase 1
A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Baltimore, MD + 4 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 2Overnight stay mentioned
Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin
National Institute on Aging (NIA)
- Location
- Baltimore, MD
- Eligibility basics
- Ages 65–120
- RecruitingHealthy volunteersPhase 1
First-in-Human Evaluation of [11C]JMJ-129-d2 for PDE4D Imaging in Healthy Volunteers
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–105
- RecruitingHealthy volunteersOvernight stay mentioned
Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 0 mo–100
- RecruitingHealthy volunteersPhase 1
Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency
National Cancer Institute (NCI)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–120
- RecruitingHealthy volunteersPhase 1
Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (SteMos1) With and Without ALFQ Adjuvant in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1/Phase 2
Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersOvernight stay mentioned
Clinical and Laboratory Study of Methylmalonic Acidemia
National Human Genome Research Institute (NHGRI)
- Location
- Bethesda, MD + 1 other US site
- Eligibility basics
- Ages 1 mo–115
- RecruitingHealthy volunteersOvernight stay mentioned
Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia
National Human Genome Research Institute (NHGRI)
- Location
- Bethesda, MD + 1 other US site
- Eligibility basics
- Ages 1 mo–100
- RecruitingHealthy volunteersPhase 1
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy Volunteers
National Heart, Lung, and Blood Institute (NHLBI)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–99
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies
National Cancer Institute (NCI)
- Location
- Bethesda, MD + 1 other US site
- Eligibility basics
- Ages 12–85
- RecruitingHealthy volunteersPhase 1/Phase 2
Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies
National Cancer Institute (NCI)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 12–120
- RecruitingHealthy volunteersPhase 1/Phase 2
The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral…
National Cancer Institute (NCI)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 12–120
- RecruitingHealthy volunteersPhase 1/Phase 2
Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and…
National Cancer Institute (NCI)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 12–120
- RecruitingHealthy volunteersPhase 1
pH1N1 Blinded Challenge Study
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Baltimore, MD + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersOvernight stay mentioned
Urinary Vitamin C Loss in Diabetic Subjects
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 2Overnight stay mentioned
Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–60 · Women only
- RecruitingHealthy volunteersPhase 1/Phase 2
Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersOvernight stay mentioned
NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 8–70
- RecruitingHealthy volunteersPhase 1
Assessment of [18F]-Fluorocellobiose ([18F]FCB) Pharmacokinetics in Healthy Volunteers and Subjects With Invasive Mold Infections
National Institutes of Health Clinical Center (CC)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–100