Mental health · Maryland
Mental health studies in Maryland
59 studies have at least one recruiting site in Maryland. Mental health research includes studies of depression, anxiety, PTSD, bipolar disorder, schizophrenia and ADHD, testing medicines, devices and talk therapies.
59 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
Tonix Pharmaceuticals, Inc.
- Location
- Rockville, MD + 25 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
Transcend Therapeutics
- Location
- Pikesville, MD + 36 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia
AbbVie
- Location
- Gaithersburg, MD + 6 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
Bristol-Myers Squibb
- Location
- Gaithersburg, MD + 39 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
52-week Open Label Safety-Tolerability Study
LB Pharmaceuticals Inc.
- Location
- Gaithersburg, MD + 22 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications
Minerva Neurosciences
- Location
- Gaithersburg, MD + 12 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 2
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Syndeio Biosciences, Inc
- Location
- Towson, MD + 22 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingPhase 3
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- Gaithersburg, MD + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
AbbVie
- Location
- Gaithersburg, MD + 46 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
atai Therapeutics, Inc.
- Location
- Baltimore, MD + 33 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
ALTO-207 in Adults With Treatment-resistant Depression (TRD)
Alto Neuroscience
- Location
- Annapolis, MD + 11 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
Neurocrine Biosciences
- Location
- Gaithersburg, MD + 20 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Study of ALTO-101 in Patients With Schizophrenia
Alto Neuroscience
- Location
- Gaithersburg, MD + 12 other US sites
- Eligibility basics
- Ages 21–55
- RecruitingHealthy volunteers
Characterization and Treatment of Adolescent Depression
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 11–25
- RecruitingHealthy volunteers
Improving Student Mental Health Through a Universal Trauma-Informed Intervention
Johns Hopkins Bloomberg School of Public Health
- Location
- Baltimore, MD + 2 other US sites
- Eligibility basics
- Ages 12–15
- RecruitingHealthy volunteersPhase 2
Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD + 1 other US site
- Eligibility basics
- Ages 8–65
- RecruitingHealthy volunteers
Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 2
Neurobiology of Suicide
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteers
Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)
National Institute on Deafness and Other Communication Disorders (NIDCD)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–99
- RecruitingHealthy volunteers
Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 10–17
- RecruitingHealthy volunteers
Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 3–99
- RecruitingHealthy volunteers
Cognitive Neurocomputational Task Reliability & Clinical Applications Consortium (CNTRACS): Study 1
Washington University School of Medicine
- Location
- Baltimore, MD + 4 other US sites
- Eligibility basics
- Ages 18–59
- RecruitingHealthy volunteers
Long-term Observation of Participants With Mood Disorders
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–99
- RecruitingHealthy volunteersPhase 4
Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity Disorder
Donald Gilbert, MD, MS, FAAN, FAAP
- Location
- Baltimore, MD + 1 other US site
- Eligibility basics
- Ages 8–12
Who these studies look for
Studies usually require a confirmed diagnosis and stable circumstances, and they monitor safety closely. If you are in crisis, contact a crisis line or emergency services rather than a study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Will joining affect my current treatment?
Some studies require changes to medicines, which the study team manages; others add to your usual care. Talk to your own clinician before making any change.