Phase 1 · Colorado
Phase 1 clinical trials in Colorado
34 studies have at least one recruiting site in Colorado. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
34 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1/Phase 2
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
4D Molecular Therapeutics
- Location
- Lakewood, CO + 19 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1
Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants
Regeneron Pharmaceuticals
- Location
- Lakewood, CO + 4 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1/Phase 2
Phase 1/2 Study of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome
Mahzi Therapeutics
- Location
- Aurora, CO + 2 other US sites
- Eligibility basics
- Ages 2–25
- RecruitingPhase 1
A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults
UCB Biopharma SRL
- Location
- Fort Collins, CO + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis
Sonoma Biotherapeutics, Inc.
- Location
- Aurora, CO + 8 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingEarly Phase 1
VTP-1000 in Adults With Celiac Disease
Barinthus Biotherapeutics
- Location
- Colorado Springs, CO + 15 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
Neurona Therapeutics
- Location
- Aurora, CO + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Study of Andecaliximab in People With Spinal Cord Injury at Risk for Bone Growth Outside of the Normal Skeleton.
Ashibio Inc
- Location
- Denver, CO
- Eligibility basics
- Ages 18–89
- RecruitingPhase 1/Phase 2
A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)
Splice Bio
- Location
- Aurora, CO + 4 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 1
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Tenaya Therapeutics
- Location
- Aurora, CO + 6 other US sites
- Eligibility basics
- Ages 18–65
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.