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Bored Studies
RecruitingAccepts healthy volunteersPhase 1

A Phase 1 Relative Bioavailability Study of a VX-581 Tablet Formulation

Vertex Pharmaceuticals Incorporated · NCT07813039

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–55 · Men only
Healthy volunteers
Accepted
Study type
Interventional · Phase 1
Target enrollment
16
US sites recruiting
1
Study start
September 23, 2026
Record last updated
October 19, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to evaluate the relative bioavailability of VX-581 tablet formulation compared to a suspension formulation along with its safety and tolerability.

Being studied: VX-581

Conditions: Cystic Fibrosis

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Key Inclusion Criteria

  • Body mass index (BMI) of 18.0 to 32.0 kilogram per meter square (kg/m\^2), inclusive
  • Total body weight of greater than (>) 50 kg
  • Nonsmoker or ex-smoker for at least 3 months before screening with current nonsmoking status confirmed by urine or blood cotinine at screening

Key Exclusion Criteria

  • History of febrile illness or other acute illness that has not fully resolved within 14 days before the first dose of study drug
  • Any condition possibly affecting drug absorption

Other protocol defined Inclusion/Exclusion criteria may apply.

Recruiting US locations

Study contacts (from the official record)

  • Medical Information · 617-341-6777 · medicalinfo@vrtx.com
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