RecruitingAccepts healthy volunteersPhase 1

A Single Ascending Dose, and Food Effect Study of ABBV-7828 in Healthy Adults

AbbVie · NCT07856706

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

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This study is to evaluate safety, tolerability, pharmacokinetics and effect of food on ABBV-7828 compared to placebo in healthy adult participants.

Being studied: ABBV-7828; Placebo for ABBV-7828

Conditions: Healthy Subjects

Copied from the official record. The study team makes the final decision at screening.

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Inclusion Criteria

Individuals between 18 to 65 years of age at the time of screening.
BMI is \<= 18.0 to >= 32.0 kg/m2.
A condition of general good health, based upon the results of a medical history, physical evaluations, vital signs, laboratory profile and a 12-lead ECG.

Exclusion Criteria

History of epilepsy, any clinically significant cardiac, respiratory (except mild asthma as a child), renal, hepatic, gastrointestinal, hematologic or psychiatric disease or disorder, or any uncontrolled medical illness.
Has any clinically significant ECG abnormalities including the following:

Evidence of 2nd or 3rd degree atrial ventricular (AV) block at screening visit or upon initial confinement
QT interval corrected for heart rate (QTc) using Fridericia's correction formula (QTcF) > 450 msec (males) or > 460 msec (females) at screening visit or upon initial confinement.
History of any clinically significant sensitivity or allergy to any medication or food.
History of or active medical condition(s) or surgical procedure(s) that might affect gastrointestinal motility, pH, or absorption.