RecruitingAccepts healthy volunteersPhase 1

A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age

Centessa Pharmaceuticals (UK) Limited · NCT07082829

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Status re-checked against ClinicalTrials.gov within the last 12 hours.

Characterize the safety, tolerability and pharmacokinetics of ORX142 following single and multiple doses.

Being studied: ORX142 Tablets; Placebo Tablets

Conditions: Excessive Daytime Sleepiness

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Key Inclusion Criteria

For Parts A, B, C, and E:

a. Participants must be at least 18 years of age and no more than 55 years of age at the Screening

a .Participants must be at least 60 years of age and no more than 80 years of age at the Screening

Key Exclusion Criteria

Presence of significant cardiac, pulmonary, gastrointestinal, hepatic, renal, hematological, malignancy, endocrine, neurological, or psychiatric disease, as determined by medical history, physical examination, and screening investigations.
History of seizure disorder, any other condition that increases the risk of seizure
Has a clinically significant sleep disorder, including insomnia or sleep apnea.