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A Study of SCAD Using Stress Contrast Echocardiography

Mayo Clinic · with National Heart, Lung, and Blood Institute (NHLBI) · NCT07178509

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
50
US sites recruiting
1
Study start
November 25, 2025
Record last updated
January 7, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contrast echocardiography.

Being studied: Stress Echocardiography with Contrast

Conditions: Spontaneous Coronary Artery Dissection

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Adult >18 years old
  • Patient has a history of spontaneous coronary artery dissection (SCAD) OR patient is healthy with no significant medical history

Exclusion Criteria

  • Unable to give consent
  • Allergic or have a history of adverse reaction to dobutamine, the Definity® ultrasound enhancing agent, or atropine.
  • Has a known or suspected hypersensitivity to perflutren and therefore cannot be given Definity®.
  • Pregnant.
  • Unable to interrupt breastfeeding.
  • Within 3 months of a heart attack.
  • Severe aortic stenosis.
  • Severe, uncontrolled hypertension (>200/110 mmHg at baseline).

Recruiting US locations

  • Mayo Clinic

    Rochester, MN 55905

    Site contact: Pamela Engrav · 507-255-6938 · engrav.pamela@mayo.edu

Study contacts (from the official record)

  • Pamela Engrav · 507-255-6938 · engrav.pamela@mayo.edu
All heart & blood pressure studies in Minnesota →
A Study of SCAD Using Stress Contrast Echocardiography (NCT07178509) | Bored Studies