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RecruitingAccepts healthy volunteersPhase 1

A Study of Ulonivirine (MK-8507) and Methadone in Healthy Volunteers (MK-8507-019)

Merck Sharp & Dohme LLC · NCT07595263

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–65 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 1
Target enrollment
14
US sites recruiting
1
Study start
August 17, 2026
Record last updated
September 23, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study is designed to determine the effect of ulonivirine (MK-8507) on methadone in the body. Participants will take methadone alone and then methadone with ulonivirine to see if ulonivirine changes how the body processes methadone.

Being studied: Ulonivirine; Methadone

Conditions: Healthy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

The main Inclusion Criteria include but are not limited to:

  • Is in good health
  • Has a body mass index (BMI) between >18 and ≤40 kg/m\^2
  • Is reliably participating in a methadone maintenance program for at least 2 months prior to Day 1 and is on a documented stable dose of methadone for at least 14 days prior to Day 1

Exclusion Criteria

The main Exclusion Criteria include but are not limited to:

  • Has a history of cancer (malignancy)
  • Has a history of significant multiple and/or severe allergies, or has had an anaphylactic reaction or significant intolerability to prescription or nonprescription drugs or food
  • Has tested positive human immunodeficiency virus (HIV) or for a sexually transmitted infection at screening
  • Is under the age of legal consent

Recruiting US locations

  • Pinnacle Research Group ( Site 0002)

    Anniston, AL 36207

    Site contact: Study Coordinator · 256-236-0055

Study contacts (from the official record)

  • Toll Free Number · 1-888-577-8839 · Trialsites@msd.com
All healthy volunteers studies in Alabama →
A Study of Ulonivirine (MK-8507) and Methadone in Healthy… (NCT07595263) | Bored Studies