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A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection

Mayo Clinic · with National Heart, Lung, and Blood Institute (NHLBI) · NCT05699200

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · Women only
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
50
US sites recruiting
1
Study start
June 1, 2023
Record last updated
June 17, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this research is to compare sympathetic function (flight or fight system) and arterial health including structure and mechanics of participants with history of spontaneous coronary artery dissection (SCAD) to age and sex matched control participants.

Being studied: Arterial Tonometry; Echocardiogram; Carotid Ultrasounds; Elastography; Ankle-Brachial Index; Microneurography with sympathoexcitatory maneuvers

Conditions: Spontaneous Coronary Artery Dissection; Healthy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • For SCAD patients: history of SCAD as confirmed by coronary angiography or cardiac computed tomography angiography
  • For controls: no cardiac disease history

Exclusion Criteria

  • Pregnancy
  • Known or suspected unstable cardiac condition within 4 weeks of the study
  • Active treatment with anticoagulation or dual antiplatelet therapy
  • Prisoner

Recruiting US locations

Study contacts (from the official record)

  • Pamela Engrav · 507-255-6938 · Engrav.Pamela@mayo.edu
A Study to Analyze the Role of Sympathetic Nervous System in… (NCT05699200) | Bored Studies