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A Study to Evaluate Breathing Muscle Training in Cardiac Rehab

Mayo Clinic · NCT04984473

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
42
US sites recruiting
1
Study start
June 1, 2021
Record last updated
July 17, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to understand if breathing muscle training combined with cardiac rehabilitation influences the blood flow and blood pressure response during exercise.

Being studied: Inspiratory muscle training

Conditions: Healthy; Heart Failure

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria - Heart Failure Group

  • Adult 18 years and older.
  • English speaking.
  • Has a qualifying heart failure indication for center-based cardiac rehabilitation.

Inclusion Criteria - Healthy Control Group:

  • Adult 18 years and older.
  • English speaking.
  • Absence of pulmonary, cardiovascular, musculoskeletal, neurologic, or orthopedic diseases. Controls will be matched for age and sex.

Exclusion Criteria

  • HF patients who are unable to engage in a regularly structured exercise training program as part of a clinically indicated center-based outpatient cardiac rehabilitation program.
  • Participants unable/unwilling to provide informed consent.
  • Uremia, history of allergy to iodides. Impaired renal function.
  • Creatinine value greater than 1.3 mg/dL (via clinical record within the past 6 months).
  • Diagnosis of liver disease.

Recruiting US locations

  • Mayo Clinic in Rochester

    Rochester, MN 55905

    Site contact: Joshua R. Smith, PhD

Study contacts (from the official record)

  • Eric Bruhn, MA · 507-266-2690 · bruhn.eric@mayo.edu
  • Joshua Smith · smith.joshua1@mayo.edu
All heart & blood pressure studies in Minnesota →
A Study to Evaluate Breathing Muscle Training in Cardiac Rehab (NCT04984473) | Bored Studies