A Study to See How Safe a New Medicine (NNC0642-1895) is in Healthy People
Novo Nordisk A/S · NCT07829406
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–55 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Phase 1
- Target enrollment
- 148
- US sites recruiting
- 1
- Study start
- September 17, 2026
- Record last updated
- October 26, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
This study is testing a new medicine, in healthy adults to assess its safety and understand how it behaves in the body. The purpose of this study is to evaluate the safety, tolerability, and how the body responds to a single dose of NNC0642-1895 in healthy adults. Participant will either get study medicine (NNC0642-1895) or placebo (a treatment that has no active medicine in it). Which treatment a participant receives is decided by chance. NNC0642-1895 is a new medicine that is being tested in humans for the first time and is not currently available for doctors to prescribe. The study will last for about 94 days (approximately 14 weeks).
Being studied: NNC0642-1895; Placebo
Conditions: Healthy Volunteers
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Male or female (sex assigned at birth, inclusive of all gender identities).
- Age 18-55 years (both inclusive) at the time of signing the informed consent.
- Body Mass Index (BMI) between 18.5 to 29.9 kilogram per square meter (kg/m\^2) (both inclusive) at screening
- Considered to be generally healthy based on the medical history, physical examination, and the results of vital signs, electrocardiogram and clinical laboratory tests performed during the screening visit, as judged by the investigator.
Exclusion Criteria
- Known or suspected hypersensitivity to study intervention(s) or related products.
- Any laboratory safety parameters at screening outside the below laboratory ranges, see designated reference range documents for specific values:
- Alanine aminotransferase (ALT) greater than (>) Upper limit of normal (ULN) +10 percent (%)
- Aspartate aminotransferase (AST) > ULN +20%
- Bilirubin > ULN +20%
- Creatinine > ULN +10%
- Absolute neutrophil count > ULN
- Absolute neutrophil count less than (\<) Lower limit of normal (LLN)
- Platelet count > ULN
- Platelet count \< LLN
- Supine blood pressure at screening outside the range of 90-139 millimeters of mercury (mmHg) for systolic or 50-89 mmHg for diastolic
- Heart rate outside the range of 50-90 beats/min at screening
- Use of prescription (except contraceptives) or non-prescription medicinal products within 14 days before screening. Occasional use of over-the-counter acetaminophen or Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) at their labelled doses is permitted.
Recruiting US locations
ICON-Salt Lake City
Salt Lake City, UT 84124
Study contacts (from the official record)
- Novo Nordisk · (+1) 866-867-7178 · clinicaltrials@novonordisk.com
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