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Acute Mental Fatigue and Muscle Strength

Florida Institute for Human and Machine Cognition · NCT07846618

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–39 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
50
US sites recruiting
1
Study start
September 23, 2026
Record last updated
September 29, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study will investigate the acute effects of mental fatigue on lower-extremity muscle strength and limb symmetry in healthy young adults. Participants will complete lower-extremity strength testing before and after a standardized computer-based mental fatigue protocol involving tasks of attention, reaction time, concentration, and working memory. Muscle strength and limb symmetry will be assessed using isokinetic dynamometry, with muscle activity measured using surface electromyography. Participants will also complete subjective measures of mental fatigue, sleepiness, mental effort, and perceived physical exertion. Heart rate will be monitored throughout the study, and brain activity may be assessed during cognitive tasks. The study will determine whether acute mental fatigue is associated with changes in muscle strength, limb symmetry, and neuromuscular performance.

Being studied: Computer-Based Mental Fatigue Protocol

Conditions: Mental Fatigue; Muscle Strength Dynamometer

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age 18-39 years
  • Able to produce maximal force against Biodex protocol
  • Able to perform required lower extremity movements through range of motion necessary for Biodex protocol
  • No known cognitive impairment
  • Sufficient musculoskeletal health to complete the tasks

Exclusion Criteria

  • History of a neurological disorder, disease, or cognitive impairment that may affect cognition, motor control, reaction time, or force production
  • History of musculoskeletal injury affecting the lower extremities within the past 6 months
  • History of lower extremity surgery affecting force production of the hip, knee, or ankle
  • Color-vision impairment
  • Significant visual or hearing impairment
  • History of migraine headaches
  • Current significant sleep disturbances or sleep deprivation
  • Head injury that may affect cognitive function
  • Medical condition affecting ability to produce maximal force safely
  • Allergy to adhesive tape, parabens, or propylene glycol
  • Scalp lacerations, open wounds, or sutures on the scalp
  • Cranial surgery or skull defects
  • History of unexplained dizziness or fainting in the past 6 months
  • Individuals who are pregnant, prisoners, or not yet adults
  • Inability to communicate with investigators
  • Inability to provide written informed consent

Recruiting US locations

  • Florida Institute for Human and Machine Cognition

    Pensacola, FL 32502

    Site contact: Nicole Rendos, PhD · 850-202-4442 · nrendos@ihmc.org

Study contacts (from the official record)

  • Nicole K Rendos, PhD · 850-202-4442 · nrendos@ihmc.org
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Acute Mental Fatigue and Muscle Strength (NCT07846618) | Bored Studies