Skip to content
Bored Studies
RecruitingAccepts healthy volunteers

ADAPT Study: Assessing Diet, Appetite and Physiology Throughout Weight Loss Study)

University of Washington · with National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · NCT06174389

View Study & Apply (opens in a new tab)

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–60 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
90
US sites recruiting
1
Study start
October 1, 2023
Record last updated
August 29, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Behavioral weight loss programs for obesity can result in weight loss and health benefits. However, behavioral weight loss often stops despite efforts to continue losing weight, this can be called an involuntarily weight loss plateau. This study investigates changes in metabolism and/or the brain that contribute to the occurrence of an involuntary weight loss plateau.

Being studied: Behavioral Weight Loss Program

Conditions: Obesity

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • BMI 30.0 - 50.0 kg/m2
  • Able to attend study intervention classes and study visits/assessments
  • Independently living with access to food preparation facilities

Exclusion Criteria

  • Current smoker or regular use of nicotine containing products and/or cannabis
  • Heavy alcohol use (≥2 drinks/d for females, ≥3 drinks/d for males) or drug use
  • Known cognitive impairments or h/o stroke
  • Type 2 diabetes (known diagnosis or by screening A1c (≥6.5%))
  • Medical conditions (chronic diseases, cancer, MS) or labs limiting ability to participate
  • Females: currently pregnant (or 6-months postpartum of full-term pregnancy) and/or current breastfeeding
  • Use of medications with significant effects on appetite (e.g., weight loss medications, atypical antipsychotics, stimulants) and/or chronic use of anticoagulants
  • History of bariatric surgery
  • History of eating disorder
  • Current participation in a formal weight loss program
  • Prior or current participation in a research study involving weight loss
  • Weight-reduced by >10% within past year
  • Weight > 330 pounds (MRI limit)
  • Allergy or intolerance to or unwillingness to consume study foods provided at visit
  • MRI contraindication (e.g., implanted metal, claustrophobia)
  • Do not have a phone compatible with activity tracker or access to videoconferencing platform that will be used for the dietary intervention or other appropriate technology needed to complete study procedures
  • Any condition(s) found by the study team and confirmed with the PI(s) that make it unsafe to participate

Recruiting US locations

  • University of Washington - South Lake Union

    Seattle, WA 98109

    Site contact: Mary Webb · uwadaptstudy@uw.edu

Study contacts (from the official record)

  • ADAPT Study · 206-616-6360 · uwadaptstudy@uw.edu
  • ADAPT Study · 206-685-1532 · uwadaptstudy@uw.edu
All weight loss studies in Washington →
ADAPT Study: Assessing Diet, Appetite and Physiology Throughout… (NCT06174389) | Bored Studies