RecruitingAccepts healthy volunteers

Adaptive Optics Retinal Imaging

National Eye Institute (NEI) · NCT02317328

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Status re-checked against ClinicalTrials.gov within the last 12 hours.

Background

By the time diseases of the retina are detected, serious damage has often already been done. Researchers want to find better ways of viewing the retina. One way called adaptive optics may help detect problems earlier.

Objectives

To study if adaptive optics can help find better ways to diagnose, treat, and manage retinal diseases.

Eligibility

Design

Participants will be screened with medical history and eye exams. These may include dilating pupils and taking pictures of the eyes.
Participants will have 1 or more study visits. They will have:
Medical and eye history.
Questions about their medications.
Eye exam including pupil dilation.
Adaptive optics imaging. After dilation, participants sit still while looking into an adaptive optics instrument. They look at specific places and images are taken of their retina.
They may also have:
More images.
Perimetry. Participants look into a lens and press a button when they see a light.
Color vision tests.
Electroretinogram. Participants will get numbing eye drops and special contact lenses. A small metal electrode will be put on their forehead. They will look at flashing lights and try not to blink.

Conditions: Eye Diseases; Healthy Volunteers

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Participants will be eligible if they

Are 12 years of age or older.
Have the ability to cooperate with an eye exam and adaptive optics imaging.
Have the ability to understand and sign an informed consent or have a parent/legal guardian to do so if they are minor children.
Have an eye disease or are a healthy volunteer with a normal eye exam (no visually-significant eye findings on examination).

EXCLUSION CRITERIA

Participants will not be eligible if

-They have a condition which prevents adequate images from being obtained (e.g. unstable fixation or media opacity).

EXCLUSION CRITERIA FOR FLUORESCEIN AND/OR INDOCYANINE GREEN IMAGING

Partaicipants are not eligible for fluorescein and/or indocyanine green imaging if they:

Are under 18 years of age.
For participants who will undergo fluorescein imaging have a history of adverse reaction to fluorescein.
For participants who will undergo indocyanine green imaging have a history of adverse reaction to indocyanine green dye, know or suspected allergies to iodine or shellfish.

National Institutes of Health Clinical Center
Bethesda, MD 20892
Site contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) · 800-411-1222 · ccopr@nih.gov