Adaptive Optics Retinal Imaging

Inclusion Criteria

• Are 21 years of age or older.
• Have the ability to cooperate with instructions during adaptive optics imaging (similar to instructions given during a clinical eye exam).
• Have the ability to understand and sign an informed consent.
• Have been diagnosed with POAG (cohort 2).

Exclusion Criteria

• Are under 21 years of age.
• Have a condition which prevents adequate images from being obtained (e.g. unstable fixation or media opacity).
• Have visual correction outside of the range +4 diopters (D) to -8 D.
• Have a history of adverse reaction to mydriatic drops.
• Have a predisposition to (i.e., narrow iridocorneal angle) or any history of acute angle closure glaucoma (AACG).
• Do not meet the criteria for POAG as defined by the American Academy of Ophthalmology Practice Patterns (cohort 2)
• Have any health conditions that would contraindicate oxygen supplementation, including chronic obstructive pulmonary disease (COPD), emphysema, asthma, or any other obstructive or restrictive lung disease (RBF experiment participants only).
• Have a dependency on oxygen support or a baseline oxygen saturation \<95% (RBF experiment participants only).
• Have tested positive for COVID-19 at initial enrollment or have acute or chronic photophobia as a result of contraction.
• Are working under the direct supervision of Dr. Hammer.