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Addressing Genomic Disparities in Cancer Survivors

Rutgers, The State University of New Jersey · with Georgetown University, National Cancer Institute (NCI) · NCT06073626

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–80 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
428
US sites recruiting
2
Study start
July 31, 2024
Record last updated
October 28, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this observational study is to increase genetic education and genetic testing for hereditary cancer risk among Black cancer survivors. The study will:

  • Test the effectiveness of a chatbot intervention (also called relational agent, or RA) vs. enhanced usual care (EUC) on engagement in genetic education and requests for genetic testing.
  • Evaluate the impact of the chatbot vs. EUC on the process that participants use to make decisions and evaluate effects on well-being (also called psychosocial outcomes).
  • Explore the ways (methods) that influence how participants experience the intervention.
  • Explore the feasibility of incorporating a Family Sharing Portal (FSP) for participants who receive a positive test result, to facilitate family communication of these test results and genetic testing of first-degree biological relatives after they have received genetic education by the RA.

The main questions this study aims to answer are which group - the chatbot (RA) group or the EUC group - is more likely to request genetic testing and which group is more likely to get (engage with) genetic education.

Participants will be randomly assigned to either the chatbot (RA) group or EUC group. This means each participant has an equal chance of being placed in either group, just like flipping a coin. Each group will receive genetic education and have an opportunity to request genetic testing. Researchers will compare the chatbot (RA) group and the EUC group to see which may request more GT (genetic testing) and which group engages more with genetic education.

Being studied: Relational agent (RA) / Chatbot; Enhanced Usual Care (EUC)

Conditions: Hereditary Cancer; Genetic Testing

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • 18-80 years of age
  • Self-identify as Black or African American
  • At least 6-months post diagnosis with any of the following cancers: breast, ovarian, uterine, prostate, colorectal, pancreatic
  • Have not had genetic testing for hereditary cancer
  • Have received care at one of the participating sites in the prior five years
  • Meet National Comprehensive Cancer Network criteria for germline GT
  • Able to read and speak in English
  • Capable of providing informed consent
  • Have internet access (via smartphone, tablet or computer)
  • Comfortable using a computer or mobile phone independently to access information

Exclusion Criteria

  • Do not speak English
  • Unable to access the Internet
  • Have previously undergone germline genetic testing for hereditary cancer risk or previously had genetic counseling (GC) and declined genetic testing (GT)
  • Are unable to provide informed consent

Recruiting US locations

  • Georgetown Lombardi Comprehensive Cancer Center

    Washington D.C., DC 20007

    Site contact: Lia Sorgen · lia.sorgen@georgetown.edu

  • Rutgers Cancer Institute

    New Brunswick, NJ 08901

    Site contact: Erin Speiser, PhD, MA · erin.speiser@rutgers.edu

Study contacts (from the official record)

  • Erin Speiser, PhD, MA · 732-675-1668 · erin.speiser@rutgers.edu
  • Julie Chapman Greene, PhD, MPH · chapmaje@cinj.rutgers.edu
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Addressing Genomic Disparities in Cancer Survivors (NCT06073626) | Bored Studies