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Adipose Tissue Blood Flow in Aging Humans

Mayo Clinic · with National Center for Advancing Translational Sciences (NCATS) · NCT06096532

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–80 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
24
US sites recruiting
1
Study start
February 15, 2024
Record last updated
May 1, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this basic science clinical trial is to understand whether adipose tissue blood flow changes between younger and older healthy adults.

The main question[s] it aims to answer are:

  • Is basal and nutrient responsive adipose tissue blood flow (ATBF) different between younger and older adults
  • What molecular and systemic signatures related to adipose tissue blood flow are altered between these two groups.

Participants will undergo measurements of adipose tissue blood flow using the xenon washout technique, undergo 2 abdominal subcutaneous adipose tissue biopsies, and drink a sugary drink.

Being studied: 75 gm oral glucose load

Conditions: Healthy; Aging

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion criteria

  • Within the ages of 18-35 years or 65-80 years at time of study visit
  • BMI between 20-25.0 kg/m2.

Exclusion criteria

  • Presence of diagnosed cardiometabolic diseases (e.g., Type 2 diabetes, hypertension, Heart Failure)
  • Taking prescription anticoagulants
  • Taking prescriptions or supplements that effect adipose tissue metabolism (i.e., statins, Thiazolidinediones, niacin, atypical antipsychotics, or fish oil)
  • Pregnant or nursing
  • Inability to provide written informed consent
  • Smokers

Recruiting US locations

  • Mayo Clinic Minnesota

    Rochester, MN 55905

    Site contact: Kelli A Lytle, PhD · 507-255-1488 · lytle.kelli@mayo.edu

All healthy volunteers studies in Minnesota →
Adipose Tissue Blood Flow in Aging Humans (NCT06096532) | Bored Studies