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RecruitingAccepts healthy volunteersPhase 4

Aging, Beta Blockers, and Thermoregulatory Responses

University of Texas Southwestern Medical Center · NCT06582680

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 65+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 4
Target enrollment
22
US sites recruiting
1
Study start
October 4, 2024
Record last updated
October 23, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study will test the hypothesis that the drugs propranolol and metoprolol will result in greater increases in core body temperature during 3 hours of extreme heat exposure in older adults.

Being studied: Ambient Heat

Conditions: Heat Stress; Aging

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Healthy and free of any significant medical problems
  • Normal resting electrocardiogram
  • 65+ years of age
  • Controlled cholesterol of less than 200 mg/dl
  • Controlled blood pressure of less than 140/90 mmHg

Exclusion Criteria

  • Known diseases or other chronic conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, uncontrolled hypertension, and uncontrolled hypercholesterolemia
  • Serious abnormalities detected on routine screening
  • Taking prescribed medications or over-the-counter medications that have known influences on either cardiac function or sweating
  • Current smokers, as well as individuals who regularly smoked within the past 3 years
  • body mass index ≥31 kg/m2

Recruiting US locations

  • IEEM Texas Health Presbyterian Hospital Dallas

    Dallas, TX 75231

    Site contact: Taysom Wallace, MS · 214-345-5022 · taysomwallace@texashealth.org

Study contacts (from the official record)

  • Erin Harper, MS · 214-345-4737 · erinharper@texashealth.org
  • Courtney Kirby, RN · 214-345-6502 · courtneykirby@texashealth.org
All healthy volunteers studies in Texas →
Aging, Beta Blockers, and Thermoregulatory Responses (NCT06582680) | Bored Studies