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An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy

M.D. Anderson Cancer Center · with National Cancer Institute (NCI) · NCT04589624

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 1
Target enrollment
42
US sites recruiting
1
Study start
August 12, 2020
Record last updated
May 22, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This trial investigates whether hyperpolarized magnetic resonance imaging (hpMRI) can predict treatment response in patients with thyroid cancer and other malignancies of the head and neck undergoing radiation therapy and/or receiving systemic therapy before surgery. An hpMRI is like a standard MRI but involves the use of an imaging contrast agent called hyperpolarized 13-C-pyruvate. Diagnostic procedures, such as hpMRI, may predict a patient's response to treatment and may help plan the best treatment.

Being studied: Hyperpolarized Carbon C 13 Pyruvate; Magnetic Resonance Imaging; Magnetic Resonance Imaging

Conditions: Thyroid Gland Carcinoma

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Be willing and able to provide informed consent
  • Be informed of the investigational nature of this study
  • Be diagnosed with thyroid cancer and other malignancies of the head and neck with intent for treatment

Exclusion Criteria

  • Have a history of severe claustrophobia
  • Have electrically, magnetically or mechanically activated implants that would preclude magnetic resonance imaging (MRI)
  • Have a history of cardiac arrhythmia
  • Have an allergy to Gadavist intravenous contrast
  • Estimated glomerular filtration rate (eGFR) \< 30
  • If female, be pregnant or breast feeding at time of consent

Recruiting US locations

  • M D Anderson Cancer Center

    Houston, TX 77030

    Site contact: Stephen Y. Lai · 713-792-6528

Study contacts (from the official record)

  • Stephen Y Lai · 713-792-6528 · sylai@mdanderson.org
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An Investigational Scan (hpMRI) for Monitoring Treatment Response… (NCT04589624) | Bored Studies