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Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy

Hugo W. Moser Research Institute at Kennedy Krieger, Inc. · with Johns Hopkins University, Mount Washington Pediatric Hospital · NCT05197946

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 8+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
300
US sites recruiting
4
Study start
December 4, 2018
Record last updated
June 29, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The investigators hope to use MRI biomarkers to identify and characterize sensorimotor network disruption patterns associated with chronic pain and sensory deficits in CP. Investigators will use existing information in the medical record as well as subjective reports from interview, physical exam data, and anatomical and functional MRI data to non-invasively identify brain injury correlates of pain and sensory deficits.

Being studied: MRI

Conditions: Cerebral Palsy; Chronic Pain

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Participants with CP (Survey-only):

Inclusion Criteria

  • Individual 8+ years of age
  • Diagnosis of cerebral palsy

Exclusion Criteria

-None

Neurotypical participants: (Survey-only):

Inclusion Criteria

  • Individual 8+ years of age
  • Adult subject able to indicate understanding and affirmative consent OR Adult/child subject unable to indicate understanding and affirmative consent AND subject assents AND LAR consents

Exclusion Criteria

-Clinically-significant neurologic or developmental diagnosis

Participants with CP (Survey and MRI):

Inclusion Criteria

  • Individual 8+ years of age
  • Adult subject able to indicate understanding and affirmative consent OR Adult subject unable to indicate understanding and affirmative consent AND subject assents AND LAR consents
  • Diagnosis of cerebral palsy
  • Clinical imaging demonstrating isolated periventricular white matter injury
  • Clinical judgment that all neurologic symptoms are attributable to non-progressive periventricular white matter injury
  • Able to lie still in scanner for 1.5 hours in at most 2 sessions and be able to have MRI

Exclusion Criteria

-None

Neurotypical participants (Survey and MRI):

Inclusion Criteria

  • Individual 8+ years of age
  • Adult subject able to indicate understanding and affirmative consent
  • Able to lie still in scanner for 1.5 hours and be able to have MRI

Exclusion Criteria

-Clinically-significant neurologic or developmental diagnosis

Recruiting US locations

  • F.M. Kirby Center

    Baltimore, MD 21205

    Site contact: Eric Chin, MD · 443-923-9141 · CPpainStudy@kennedykrieger.org

  • Mt. Washington Pediatric Hospital

    Baltimore, MD 21209

    Site contact: Stephen Nichols, MD · 410-578-8600 · snichols@mwph.org

  • Johns Hopkins Hospital

    Baltimore, MD 21287

    Site contact: Shenandoah Robinson, MD · 667-208-9378 · srobin81@jhmi.edu

  • Kennedy Krieger Institute

    Baltimore, MD 21287

    Site contact: Eric Chin, MD · 443-923-9141 · chine@kennedykrieger.org

Study contacts (from the official record)

  • Paul Salib, MS · (443) 923-9272 · CPpainStudy@kennedykrieger.org
  • Eric Chin, MD · (443) 923-9141 · CPpainStudy@kennedykrieger.org
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