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Behavioral and Neural Representations of Subjective Effort Cost

Hugo W. Moser Research Institute at Kennedy Krieger, Inc. · with National Institute of Mental Health (NIMH) · NCT04041154

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–35 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
185
US sites recruiting
1
Study start
August 1, 2018
Record last updated
January 26, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this proposal is to understand the common and distinct behavioral and neural representations of subjective effort valuation, and how these representations are influenced by fatigue and changes in motivation. It is hypothesized that the brain will use overlapping and distinct neural circuits to represent cognitive and physical effort value, and that fatigue and enhanced motivation will influence the subjective value of effort.

Being studied: Cognitive Fatigue; Physical Fatigue; Rewarding Stimuli

Conditions: Fatigue

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Right-handed
  • Age between 18 and 35 years old - Male or female
  • Any ethnicity

Exclusion Criteria

Individuals with a history of any of the following will be excluded from the study:

  • Neurological problems such as stroke, head injury, epilepsy, seizures, brain tumors, brain surgery, Parkinson's Disease (self- report)
  • Diagnosed history of severe psychiatric disease such as depression, schizophrenia (self-report)
  • Metal in the head or eyes
  • If they are pregnant or suspect that you may be pregnant
  • If they experience discomfort from the MRI scan, such as severe claustrophobia or excessive heating of tattoos

Recruiting US locations

  • Kennedy Krieger Institute

    Baltimore, MD 21209

    Site contact: Anthony Gonzalez · 443-923-2716 · gonzalezan@kennedykrieger.org

Study contacts (from the official record)

  • Anthony Gonzalez · 443-923-2716 · gonzalezan@kennedykrieger.org
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Behavioral and Neural Representations of Subjective Effort Cost (NCT04041154) | Bored Studies