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Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

University of Minnesota · NCT07069478

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 21–70 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
125
US sites recruiting
1
Study start
June 16, 2025
Record last updated
July 22, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The aim of this study is to determine the effects of regular cannabidiol (CBD) use on the psychobiological mechanisms of the stress response. This will be achieved by comparing acute stress responses of adults who either use or do not use CBD regularly. Correlates of CBD use, including tobacco use, will be collected.

Being studied: Stress Intervention

Conditions: CBD; Cannabidiol; Stress; Acute Stress Reaction

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Adults who are relatively healthy and aged 21-70 years.
  • Must keep a normal sleep schedule (sleep during nighttime, awake during daytime).
  • Must either (1) use CBD daily/regularly or (2) not use CBD regularly.

Exclusion Criteria

  • Participated in previous acute stress studies that included a similar stress induction.
  • Current, unstable: major psychiatric disorder or medical condition (e.g., uncontrolled hypertension above 160/100).
  • Self-reported current pregnancy.
  • Self-reported current use of illicit substances (other than cannabis).
  • Non-compliance with instructions for study visit (abstinence from alcohol, caffeine, physical activity, etc.)
  • Students of the principal researcher

Recruiting US locations

  • University of Minnesota

    Minneapolis, MN 55455

    Site contact: Stress and Resilience Research Labs · 218-726-8623 · umdbml@d.umn.edu

Study contacts (from the official record)

  • Stress and Resilience Research Labs · 2187268623 · umdbml@d.umn.edu
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Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms (NCT07069478) | Bored Studies