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Cannabis' Impact on Alcohol Consumption

Brown University · with National Institute on Alcohol Abuse and Alcoholism (NIAAA) · NCT05389930

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 21–50 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 2
Target enrollment
350
US sites recruiting
1
Study start
March 16, 2023
Record last updated
October 5, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which participants choose either to drink or receive monetary reinforcement for drinks not consumed. Cannabis will be administered simultaneously with an alcohol-priming dose or alcohol placebo.

The study will enroll up to 350 nontreatment-seeking heavy episodic alcohol drinkers who use cannabis weekly.

Being studied: THC-dominant cannabis; CBD-dominant cannabis; Cannabis placebo; Alcohol; Alcohol placebo

Conditions: Alcohol Drinking; Cannabis Use; Cannabis; Alcohol Use Disorder

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age 21 to 50
  • English-speaking
  • cannabis smoking in past two months
  • heavy drinking in past two months
  • in good physical health and weighing \< 250 lbs
  • zero breath alcohol at each visit

Exclusion Criteria

  • positive pregnancy test
  • nursing
  • positive urine toxicology screen for drugs other than cannabis
  • interest to quit or receive treatment for cannabis or alcohol use

Recruiting US locations

  • Brown University

    Providence, RI 02912

    Site contact: Jane Metrik, PhD · 401-863-6650 · Jane_Metrik@brown.edu

Study contacts (from the official record)

  • Jane Metrik, PhD · 401-863-6650 · Jane_Metrik@brown.edu
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Cannabis' Impact on Alcohol Consumption (NCT05389930) | Bored Studies