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CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study

Mayo Clinic · NCT06220396

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 30+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
80
US sites recruiting
1
Study start
January 22, 2026
Record last updated
August 14, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to evaluate pulmonary capillary wedge pressure (PCWP) and other hemodynamic measurements at rest and during exercise in healthy volunteers across the age spectrum.

Being studied: Right Heart Catheterization with Hemodynamics and Limited Echocardiogram; Magnetic Resonance Imaging (MRI); Dual X-ray absorptiometry (DEXA) scan

Conditions: Healthy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Apparently healthy volunteers are eligible to participate in this study if they are free of symptoms of exertional breathlessness or fatigue and any diagnosis of heart failure.
  • Patients will also be required to have left ventricular ejection fraction (EF) ≥ 50%.
  • Patients discovered to reduced EF or abnormal resting hemodynamics or other pathologic findings previously undiscovered will be considered screen failures and can be replaced by others to reach the goal enrollment.
  • Informed consent were obtained.
  • No history of heart failure.
  • Willing and able to undergo invasive hemodynamic exercise testing, MRI, and other study assessments.

Exclusion Criteria

  • Clinically significant symptoms of exertional dyspnea or fatigue in daily life in the opinion of the investigators.
  • Any diagnosis of heart failure
  • Symptomatic coronary artery disease (e.g., patients with chronic angina)
  • Symptomatic valvular heart disease
  • Pulmonary hypertension
  • Cardiomyopathies
  • High output heart failure
  • Pericardial disease
  • Clinically significant chronic lung disease in the opinion of the investigators
  • Anemia (hemoglobin \<12 gm/dL in women and \<13 gm/dL in men)
  • Estimated glomerular filtration rate ≤30mL/min
  • Pregnant women
  • Any other disorders or problems that would interfere with the ability to participate safely in the study (e.g. psychiatric disorder or substance abuse)

Recruiting US locations

  • Mayo Clinic in Rochester

    Rochester, MN 55905

    Site contact: Dr. Borlaug's Research Team · (507) 255-2200

Study contacts (from the official record)

  • Brendon Urena · 507-538-8305 · Urena.brendon@mayo.edu
  • Barry Borlaug, MD · Borlaug.Barry@mayo.edu
All healthy volunteers studies in Minnesota →
CArdioMEtabolic Function and Reserve Capacity in Healthy Adults:… (NCT06220396) | Bored Studies