Cardiovascular Effects of Grieving
University of South Florida · with Arizona State University · NCT07356635
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 140
- US sites recruiting
- 1
- Study start
- October 16, 2025
- Record last updated
- January 21, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
Self-affirmation (SA) theory proposes that people are motivated to maintain a positive self-image of being worthy, stable, and capable. Self-affirmation (SA) manipulations have been shown to effectively increase self-worth as well as reduce cardiovascular reactivity while enhancing cardiovascular recovery in response to stress. While SA is discussed as a way to alleviate grief, its effect on cardiovascular reactivity (CVR) and recovery to grief recall has yet to be studied within laboratory settings. This study proposes an experimental design to examine how an in-lab manipulation promoting self-affirmation can improve patients' cardiovascular responses during and after a grief recall procedure. The investigators hypothesized that grief severity (a continuous variable) interacts with condition (a categorical variable with two levels, i.e., SA intervention vs. control) to predict CV reactivity and recovery as outcomes.
Primary Objective 1: To investigate effects of self-affirmation intervention on cardiovascular responses among grieving participants during and after grief recall.
Secondary Objective 1: To investigate the relationship of grief severity with psychological stress.
Being studied: Value-affirmation
Conditions: Grief; Cardiovascular Health; Emotion
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Individuals aged 18 and older who have experienced the death of family member and/or friend within the last 2 to 18 months.
- Participants must also be fluent in English as all procedures will be conducted in English.
Exclusion Criteria
- Individuals with a history of cardiovascular disease or disorders, those who report being pregnant, or are taking medication which may alter/affect cardiovascular and/or cognitive processes.
Recruiting US locations
University of South Florida, Psychology and Communication Sciences and Disorders Lab Building
Tampa, FL 33620
Site contact: Kaiyuan Luo, BS, BA · 412-708-9227 · kluo@usf.edu
Study contacts (from the official record)
- Kaiyuan Luo, BS, BA · 412-708-9227 · kluo@usf.edu
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