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Cardiovascular Effects of Grieving

University of South Florida · with Arizona State University · NCT07356635

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
140
US sites recruiting
1
Study start
October 16, 2025
Record last updated
January 21, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Self-affirmation (SA) theory proposes that people are motivated to maintain a positive self-image of being worthy, stable, and capable. Self-affirmation (SA) manipulations have been shown to effectively increase self-worth as well as reduce cardiovascular reactivity while enhancing cardiovascular recovery in response to stress. While SA is discussed as a way to alleviate grief, its effect on cardiovascular reactivity (CVR) and recovery to grief recall has yet to be studied within laboratory settings. This study proposes an experimental design to examine how an in-lab manipulation promoting self-affirmation can improve patients' cardiovascular responses during and after a grief recall procedure. The investigators hypothesized that grief severity (a continuous variable) interacts with condition (a categorical variable with two levels, i.e., SA intervention vs. control) to predict CV reactivity and recovery as outcomes.

Primary Objective 1: To investigate effects of self-affirmation intervention on cardiovascular responses among grieving participants during and after grief recall.

Secondary Objective 1: To investigate the relationship of grief severity with psychological stress.

Being studied: Value-affirmation

Conditions: Grief; Cardiovascular Health; Emotion

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Individuals aged 18 and older who have experienced the death of family member and/or friend within the last 2 to 18 months.
  • Participants must also be fluent in English as all procedures will be conducted in English.

Exclusion Criteria

  • Individuals with a history of cardiovascular disease or disorders, those who report being pregnant, or are taking medication which may alter/affect cardiovascular and/or cognitive processes.

Recruiting US locations

  • University of South Florida, Psychology and Communication Sciences and Disorders Lab Building

    Tampa, FL 33620

    Site contact: Kaiyuan Luo, BS, BA · 412-708-9227 · kluo@usf.edu

Study contacts (from the official record)

  • Kaiyuan Luo, BS, BA · 412-708-9227 · kluo@usf.edu
Cardiovascular Effects of Grieving (NCT07356635) | Bored Studies