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Communicating About Nicotine Reduction in Cigarettes

Georgia State University · with Emory University, University of South Carolina · NCT06787937

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 21+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
1230
US sites recruiting
2
Study start
September 11, 2025
Record last updated
October 29, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this clinical trial is to learn how a messaging campaign about reduced nicotine cigarettes and policy, combined with the use of very low nicotine cigarettes (VLNCs), affects smoking behavior and attitudes among adult smokers. The study also aims to assess the efficacy of the messages in different populations, including smokers with past-month serious psychological distress (SPD), low socioeconomic status (SES), and those in neither category.

The primary hypothesis is: exposure to messages in combination with VLNC use will lead to less cigarettes use compared to VLNCs without messages.

Researchers will compare: The effects of receiving VLNCs with messages (treatment group) to receiving VLNCs without messages (control group).

Participants will: Complete a baseline survey and be randomly assigned to one of two groups: treatment (VLNCs + messages) or control (VLNCs only). Attend weekly study visits for surveys, breath samples, and receive supply of VLNCs , either with or without the messaging campaign. Complete brief daily surveys through text messages.

Being studied: VLNC messages; Control message

Conditions: Tobacco Products; Smoking Behavior; Cigarette Use

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age 21+ years
  • Current smoker (self-report as having smoked 100 cigarettes in their lifetime and currently smoking on 27+ days out of past 30, expired breath carbon monoxide [CO] ≥6ppm to assess regular smoking)
  • Can speak, read, and write in English
  • Available for period of study
  • Willing to try novel research cigarettes

Exclusion Criteria

  • Pregnancy or lactation
  • Member of the same household as a study subject
  • Unwilling to use research cigarettes as part of the trial

Recruiting US locations

  • Georgia State university

    Atlanta, GA 30303

    Site contact: Lyudmila Popova, Ph.D. · 404-413-9338 · lpopova1@gsu.edu

  • Emory University

    Atlanta, GA 30322

    Site contact: Nicholas Giordano, Ph.D. · 404-727-7980 · nicholas.a.giordano@emory.edu

Study contacts (from the official record)

  • Lyudmila Popova, Ph.D. · 404-413-9338 · lpopova1@gsu.edu
All smoking & vaping studies in Georgia →
Communicating About Nicotine Reduction in Cigarettes (NCT06787937) | Bored Studies