Comparison of Two Quantitative EMG Monitors for Deep Neuromuscular Block in Laparoscopic/Robotic and VATS Surgery
Ohio State University · NCT07706504
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 35
- US sites recruiting
- 1
- Study start
- February 9, 2026
- Record last updated
- July 15, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The main objective of the study is to compare the frequency of intraoperative spontaneous diaphragmatic movements and breath-initiation efforts in participants undergoing robotic and/or thoracic surgery under deep neuromuscular blockade (NMB), using either the TetraGraph or TwitchView applied to the dominant hand. These events will serve as objective indicators to evaluate each device's ability to monitor and maintain adequate deep NMB.
Being studied: TetraGraph (Senzime)-Guided Neuromuscular Monitoring (Dominant Hand); TwitchView (Blink)-Guided Neuromuscular Monitoring (Dominant Hand)
Conditions: Neuromuscular Blockade
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Adult male or female patients aged ≥ 18 years old.
- Patients undergo elective abdominal laparoscopic/robotic or thoracic video-assisted (VAT) surgeries requiring general anesthesia for greater than 3 hours at The Ohio State University Wexner Medical Center.
- Able to provide a signed, written informed consent.
- Able to speak, read, and write in English.
- ASA physical status I-III.
Exclusion Criteria
- Patients who require emergency surgery or an emergent intervention.
- Any documented cognitive or psychological disorders that, in the investigator's opinion, can interfere with the patient's pain perception.
- Vulnerable populations: pregnant females, prisoners, breastfeeding.
- Presence of any medical condition that, in the opinion of the principal investigator, should exclude the patient from the study (patients with pre-existing neuromuscular diseases.
- Allergy or contraindications to any of the anesthetics, NMB agents, or sugammadex.
- Patients with anatomical abnormalities of the hands or arms that prevent proper placement of the sensors for nerve stimulation.
- Limited access to the monitoring area due to surgical positioning.
- Patients with peripheral vascular disease, since it may affect measurement accuracy.
Recruiting US locations
The Ohio State University Wexner Medical Center
Columbus, OH 43201
Site contact: Alberto Uribe, MD · 614-293-0775 · alberto.uribe@osumc.edu
Study contacts (from the official record)
- Alberto Uribe, MD · 6142933559 · alberto.uribe@Osumc.edu
- Elvia Vera, MD · 6142933559 · Elvia.VeraMiquilena@osumc.edu
Similar studies in Ohio
All healthy volunteers studies in Ohio →- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Single and Multiple Ascending Dose Study of HM17321 in Healthy and Obese Participants
Hanmi Pharmaceutical Company Limited
- Location
- Cincinnati, OH
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
LH-001 vs Placebo in Healthy Participants
Chien-Liang Lin
- Location
- Columbus, OH
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study of BLB-201 RSV Vaccine in Infants and Children
Blue Lake Biotechnology Inc.
- Location
- Beachwood, OH + 13 other US sites
- Eligibility basics
- Ages 6 mo–5
- RecruitingHealthy volunteersPhase 1
A Study of V132 in Healthy Older Participants (V132-001)
Merck Sharp & Dohme LLC
- Location
- Columbus, OH + 9 other US sites
- Eligibility basics
- Ages 50–75