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Corneal Elastography and Patient Specific Modeling

The Cleveland Clinic · NCT03030755

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 16–80 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
60
US sites recruiting
1
Study start
May 2016
Record last updated
June 3, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this research is to develop measurement tools and simulation technology for characterizing and predicting individual responses to corneal treatments and for advancing understanding of corneal ectasia risk factors. Patients who either 1) have keratoconus and are being evaluated for corneal crosslinking or 2) have refractive error and are being evaluated for refractive surgery procedures such as LASIK will have their eyes imaged to assess their mechanical properties and will have computational simulations performed to predict the response to treatment. One aim of the study is to test the hypothesis that computational models can predict the cornea's shape changes within clinically acceptable limits of error.

Being studied: Optical coherence tomography

Conditions: Cornea; Ectasia; Refractive Errors; Keratoconus

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Any patient with keratoconus diagnosed by standard criteria, including topographic steepness, irregular astigmatism with a pattern consistent with keratoconus.
  • Any patient deemed a candidate for LASIK (laser vision correction) and scheduled for surgery.

Exclusion Criteria

  • Inability to provide informed consent, including non-English speaking (if interpreter not available) and cognitively/mentally impaired (if legal guardian not available).

Recruiting US locations

  • Cleveland Clinic Foundation Cole Eye Institute

    Cleveland, OH 44195

    Site contact: Pamela Hoffman, MS · 216-445-5248 · moorehp@ccf.org

Study contacts (from the official record)

  • Pamela Hoffman, MS · 216-445-5248 · moorehp@ccf.org
  • Rachel Rusnak · 216-445-1256 · rusnakr@ccf.org
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Corneal Elastography and Patient Specific Modeling (NCT03030755) | Bored Studies