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RecruitingAccepts healthy volunteersPhase 1/Phase 2

Curcumin and Retinal Study

Texas Tech University Health Sciences Center · NCT05774704

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 40–89 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 1, Phase 2
Target enrollment
60
US sites recruiting
1
Study start
August 21, 2023
Record last updated
January 13, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

To test how two weeks of curcumin supplementation would cross the blood brain barrier (BBB) and attach to amyloid beta proteins, to assess the feasibility (safety and bioavailability), and to explore the resulting abundance/composition of gut microbiota.

Being studied: Low curcumin group; High curcumin group

Conditions: Bioavailability; Gut Microbiome; Safety

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion

  • Both male and female, age 40 - 89 years.
  • Diagnosed with Aβ deposits in retina (peripheral superior quadrants)--to be confirmed after consent obtained. If there is documentation the potential participant has been diagnosed with Aβ deposits in retina within 6 months before the consent session, we will use this diagnosis/documentation for eligibility criteria. Otherwise, the ophthalmic exam will be repeated after consent is obtained for the study.
  • No pre-existing liver or kidney diseases by self-report.

Exclusion

  • Patients with ocular diseases (macular degeneration, severe diabetes retinopathy)
  • Had used systemic antibiotics within 1 month prior to the start of the study intervention
  • Had taken any turmeric or curcumin products within 2 weeks prior to the start of the study intervention
  • Had a known allergy to black pepper
  • Women that are pregnant or breastfeeding

Recruiting US locations

  • Texas Tech University Health Sciences Center

    Lubbock, TX 79430

    Site contact: Chwan-Li (Leslie) Shen, PhD · 806-743-2815 · Leslie.Shen@ttuhsc.edu

Study contacts (from the official record)

  • Chwan-Li (Leslie) Shen, PhD · 8067432815 · leslie.shen@ttuhsc.edu
All healthy volunteers studies in Texas →
Curcumin and Retinal Study (NCT05774704) | Bored Studies