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RecruitingAccepts healthy volunteersPhase 4

Disparities in Emergency Contraceptive Metabolism Dictate Efficacy

Oregon Health and Science University · with Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · NCT05674513

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–40 · Women only
Healthy volunteers
Accepted
Study type
Interventional · Phase 4
Target enrollment
140
US sites recruiting
1
Study start
January 9, 2023
Record last updated
July 9, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not. The investigators want to learn if genetic differences impact the risk of emergency contraception failure.

Being studied: Ulipristal acetate

Conditions: Contraceptive Usage

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Generally healthy women
  • Aged 18-40
  • regular menses (every 21-35 days) experiencing ovulatory cycles proven by a single progesterone level of 3 ng/mL or greater during the luteal phase of the screening cycle.

Exclusion Criteria

  • Pregnant, seeking pregnancy, or breastfeeding
  • Known allergy to study medication
  • Recent use of hormonal contraception
  • Irregular periods (\<21 days or >35 day cycles)
  • Routine use of nonsteroidal anti-inflammatory drugs
  • Metabolic disorders
  • Smoking
  • Any condition that would preclude the provision of informed consent
  • Using drugs (within 2 weeks of study enrollment) known to interfere with the metabolism of UPA as well as drugs known to be CYP3A4 inducers, inhibitors, or CYP3A drug substrates

Recruiting US locations

Study contacts (from the official record)

  • Women's Health Research Unit Department of OB/GYN · 503-494-3666 · whru@ohsu.edu
Disparities in Emergency Contraceptive Metabolism Dictate Efficacy (NCT05674513) | Bored Studies