Disparities in Emergency Contraceptive Metabolism Dictate Efficacy
Oregon Health and Science University · with Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · NCT05674513
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–40 · Women only
- Healthy volunteers
- Accepted
- Study type
- Interventional · Phase 4
- Target enrollment
- 140
- US sites recruiting
- 1
- Study start
- January 9, 2023
- Record last updated
- July 9, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The purpose of this study is to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not. The investigators want to learn if genetic differences impact the risk of emergency contraception failure.
Being studied: Ulipristal acetate
Conditions: Contraceptive Usage
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Generally healthy women
- Aged 18-40
- regular menses (every 21-35 days) experiencing ovulatory cycles proven by a single progesterone level of 3 ng/mL or greater during the luteal phase of the screening cycle.
Exclusion Criteria
- Pregnant, seeking pregnancy, or breastfeeding
- Known allergy to study medication
- Recent use of hormonal contraception
- Irregular periods (\<21 days or >35 day cycles)
- Routine use of nonsteroidal anti-inflammatory drugs
- Metabolic disorders
- Smoking
- Any condition that would preclude the provision of informed consent
- Using drugs (within 2 weeks of study enrollment) known to interfere with the metabolism of UPA as well as drugs known to be CYP3A4 inducers, inhibitors, or CYP3A drug substrates
Recruiting US locations
OHSU
Portland, OR 97239
Study contacts (from the official record)
- Women's Health Research Unit Department of OB/GYN · 503-494-3666 · whru@ohsu.edu
Similar studies in Oregon
All women’s health studies in Oregon →- RecruitingPhase 2
A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea
Regeneron Pharmaceuticals
- Location
- Portland, OR + 9 other US sites
- Eligibility basics
- Ages 18–40 · Women only
- RecruitingPhase 3
Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.
Granata Bio Corporation
- Location
- Portland, OR + 14 other US sites
- Eligibility basics
- Ages 18–42 · Women only