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RecruitingAccepts healthy volunteersPhase 1

Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone

Atea Pharmaceuticals, Inc. · NCT07314346

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–65 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 1
Target enrollment
32
US sites recruiting
3
Study start
January 7, 2025
Record last updated
July 16, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Drug-drug interaction study between Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone

Being studied: Buprenorphine/Naloxone + BEM/RZR; Methadone +BEM/RZR

Conditions: Healthy Volunteer Study

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Must agree to use acceptable contraceptive methods through at least 90 days after the last dose of study drug.
  • Minimum body weight of 50 kg and body mass index (BMI) of 18-32 kg/ m2.
  • Willing to comply with the study requirements and to provide written informed consent.

Exclusion Criteria

  • Infected with hepatitis B virus, hepatitis C virus, HIV.
  • Abuse of alcohol or drugs.
  • Use of other investigational drugs within 28 days prior to Day -5.
  • Concomitant use of prescription medications, or systemic over-the-counter medications (apart from methadone or buprenorphine/naloxone as assigned maintenance therapy).
  • Other clinically significant medical conditions or laboratory abnormalities.

Recruiting US locations

  • Atea Study Site

    Hollywood, FL 33019

    Site contact: Atea Study Clinical Trials Administrator · 888-481-1607 · ateaclinicaltrials@ateapharma.com

  • Atea Study Site

    Overland Park, KS 66212

    Site contact: Atea Study Clinical Trials Administrator · 888-481-1607 · ateaclinicaltrials@ateapharma.com

  • Atea Study Site

    Marlton, NJ 08053

    Site contact: Atea Study Clinical Trials Administrator · 888-481-1607 · ateaclinicaltrials@ateapharma.com

Study contacts (from the official record)

  • Atea Study Clinical Trials Administrator · 888-481-1607 · ateaclinicaltrials@ateapharma.com
Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR)… (NCT07314346) | Bored Studies