Skip to content
Bored Studies
RecruitingAccepts healthy volunteers

e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most

Johns Hopkins University · with National Institute on Aging (NIA) · NCT07454824

View Study & Apply (opens in a new tab)

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 65+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
100
US sites recruiting
1
Study start
April 15, 2026
Record last updated
June 16, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The overarching goal of this study is to pilot an intervention in which older adults with mild cognitive impairment and dementia and the older adult's care partners are identified in primary care and provided with educational materials through the patient portal to engage the participant in deprescribing. The multicomponent intervention, e-Align, includes delivery of educational information through the patient portal, and a pharmacist-led intervention to align medications with patient and care partner goals and reduce use of central nervous system (CNS) potentially inappropriate medicines (PIM). This work will establish the preliminary data, methods, and partnerships to undertake a multisite embedded pragmatic clinical trial. The resulting triadic-based behavioral intervention will promote patient and care partner engagement, and foster care that aligns with patients' values, and promote improved health and well-being outcomes for people with cognitive impairment and the patient's care partners through deprescribing.

Being studied: e-ALIGN Patient-Portal Deprescribing

Conditions: Dementia; Potentially Inappropriate Medication Use; Mild Cognitive Impairment (MCI)

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Patients: Age ≥65, with a diagnosis of MCI or dementia based on ICD-10 codes and ≥1 active CNS-PIM, who are active patient portal users.

Care partners

  • Family or other companions >21 years who regularly help the patient with managing medications.

Exclusion Criteria

  • As the trial will be based in primary care, individuals residing in long term care facilities or enrolled in hospice will be excluded.

Recruiting US locations

  • Johns Hopkins Community Physicians

    Baltimore, MD 21209

    Site contact: Ariel Green, MD, MPH, PhD

Study contacts (from the official record)

  • Ariel Green, MD, MPH, PhD · 410-550-6733 · ariel@jhmi.edu
All neurology studies in Maryland →
e-ALIGN: A Patient Portal-based Intervention to Align Medications… (NCT07454824) | Bored Studies