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Effect of Force Magnitude on Canine Retraction and Gingival Crevicular Fluid Proteome

UConn Health · with Charles Burstone Foundation · NCT06668194

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 11–16 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
40
US sites recruiting
1
Study start
November 13, 2024
Record last updated
November 26, 2024

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study aims to examine the effect of force levels in orthodontic treatment during canine retraction. Force levels refer to the pressure applied by the orthodontic devices to move teeth. Data collection will include gingival fluid, dental molds from a digital scanner, and x-rays of the upper canine region on both sides of the mouth during treatment. The null hypothesis to be tested is that there is no significant difference in the rate of canine movement between the light force and the heavy force levels.

Being studied: Light Force (150g Niti Coil); Heavy Force (400 g Niti coil)

Conditions: Tooth Crowding

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Healthy patient, non-smoker
  • Age: 11 - 16 years of age, inclusive.
  • A full complement of dentition (central incisor to 1st molar) in the four quadrants, except second molars
  • Patients requiring at least upper bilaterally maxillary 1st premolar extraction as a treatment plan (Class I bimaxillary protrusion/ crowding or Class II maxillary dentoalveolar protrusion/ crowding)
  • At least 5 mm of space left between canine and 2nd premolar to be closed at the time of canine retraction
  • At least six months after the extraction of first premolars and in a 0.019 x 0.025-inch stainless steel archwire in the maxilla
  • The ability to read and understand English and to provide informed consent

Exclusion Criteria

  • Patients under 11 years of age and over the age of 16.
  • Non-extraction treatment plan
  • Extraction of maxillary tooth other than first premolars bilaterally.
  • Evidence of poor oral hygiene
  • Evidence of previous root resorption
  • Missing or impacted tooth in any of the quadrant except 3rd molars.
  • Medical issues that affect tooth movement
  • Inability to provide oral and written consent to participate.
  • Patient on medications that may alter bone metabolisms like bisphosphonates, oral contraceptives, or PTH (parathyroid hormone)
  • Chronic illness or syndromic patients.
  • Pregnant women, prisoners, and decisional impaired

Recruiting US locations

  • Department of Orthodontics

    Farmington, CT 06032

    Site contact: Flavio Uribe, DDS, MDentSc · 860-679-2664 · furibe@uchc.edu

Study contacts (from the official record)

  • Flavio Uribe, DDS, MDentSc · 860-679-2664 · furibe@uchc.edu
  • Georgiana Defilio · 860-679-2550
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Effect of Force Magnitude on Canine Retraction and Gingival… (NCT06668194) | Bored Studies