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RecruitingAccepts healthy volunteersEarly Phase 1

Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift

University of Virginia · NCT05701969

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Early Phase 1
Target enrollment
50
US sites recruiting
1
Study start
May 30, 2022
Record last updated
May 4, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Anesthesiology residency requires extended and overnight shifts, which may negatively impact the quantity and quality of sleep.

Previous studies have investigated the effect of night float shift work on anesthesiology resident sleep and performance and demonstrated that total sleep quantity and time spent in deep and rapid eye movement (REM) sleep were significantly reduced during night float and did not return to baseline after 3 nights of recovery.

Melatonin is a hormone produced by the pineal gland, which regulates the circadian rhythm that governs sleep. Exogenous melatonin may be used as a sleep aid and is available over the counter in the United States. Melatonin is effective in realigning the circadian rhythm disorder caused by night shift work and increasing sleep duration; however, melatonin's effect on improving sleep in resident trainees has not been investigated. The investigators propose a prospective double-blinded randomized control trial to investigate the effect of melatonin on sleep quantity and quality in resident physicians assigned to a night float system.

Being studied: Melatonin; Placebo

Conditions: Sleep Disorders, Circadian Rhythm

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Post-Graduate Year 1-5
  • Current enrollment in anesthesiology, general surgery, obstetrics and gynecology, general medicine, or pediatrics residency at the Unversity of Virginia

Exclusion Criteria

  • Current use of sleep aids
  • Diagnosed sleep disorder
  • History of a pacemaker or other medical device.
  • pregnant or breast-feeding females
  • Bleeding disorders
  • Depression
  • High blood pressure
  • Seizure disorders
  • History of transplant on immunosuppression therapy.

Recruiting US locations

  • University of Virginia

    Charlottesville, VA 22908-0710

    Site contact: Keita Ikeda, PhD · 9195931174 · ki2d@uvahealth.org

Study contacts (from the official record)

  • Keita Ikeda, PH.D. · 9195931174 · ki2d@uvahealth.org
  • Emily Chuang, MA · 7575348912 · QGZ2TK@uvahealth.org
All sleep studies in Virginia →
Effect of Melatonin on Sleep Patterns of Resident Trainees During… (NCT05701969) | Bored Studies