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Effect of Product Characteristics on the Abuse Liability of Nicotine Pouches

Emory University · with National Institute on Drug Abuse (NIDA) · NCT07165808

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 21–35 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
84
US sites recruiting
1
Study start
February 13, 2026
Record last updated
February 27, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this study is to assess the effects of nicotine concentration and its interplay with pH on sensory experience, product appeal, and abuse liability of NPs among young adults NP users.

Primary objective is to assess the effect of variation in nicotine concentration in nicotine pouches (NPs) and its interaction effect with pH level on three proximal outcomes of relevance to regulation: (1) sensory experience, (2) product appeal, and (3) abuse liability of NPs.

Being studied: Nicotine pouch: Low dose; Nicotine pouch: High dose; Low pH; High pH

Conditions: Nicotine Addiction

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Current established users of nicotine pouches (have used nicotine pouches in the past 30 days \& currently use nicotine pouches every day or someday)
  • Positive cotinine test via saliva test strip
  • Those who are unmotivated to quit nicotine use
  • Read and speak English.
  • Poly-users of nicotine pouches, e-cigarettes (e.g., vape ≥20 days/month), and tobacco (e.g., ≥4 cigarettes/day for ≥2 years) will be eligible for participation

Exclusion Criteria

  • Planning to cut down or quit using nicotine in the next 30 days
  • Currently pregnant or breastfeeding
  • History of stroke, seizures, high blood pressure, heart disease/problems, or cardiovascular disease contraindications for nicotine.

Recruiting US locations

Study contacts (from the official record)

  • Dae Hee Han, PhD · 404-727-8742 · dae.hee.han@emory.edu
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Effect of Product Characteristics on the Abuse Liability of… (NCT07165808) | Bored Studies