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RecruitingAccepts healthy volunteersPhase 2

Effect of TXA on Reducing Bruising After Filler Injection

University of Wisconsin, Madison · NCT06665594

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–89 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 2
Target enrollment
40
US sites recruiting
1
Study start
December 5, 2025
Record last updated
July 23, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this clinical trial is to look at the effect tranexamic acid (TXA) may have on reducing bruising, swelling, and pain after facial filler injection. The main question it aims to answer is:

  • Does the addition of TXA to hyaluronic acid (HA) reduce bruising, swelling, and tenderness after HA injection?

Participants will receive the study medication along with the standard facial filler injection and complete surveys.

Being studied: Hyaluronic Acid (HA); Tranexamic Acid (TXA); Saline (placebo)

Conditions: Facial Filler Injections; Hyaluronic Acid; Tranexamic Acid

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age equal to or greater than 18 but less than or equal to 89 years.
  • Participants interested in facial filler (HA) injection.
  • English speaking.

Exclusion Criteria

  • Minors or under the age of 18
  • Participant over the age of 89
  • Pregnant or breast-feeding women
  • Individuals unable to give consent due to another condition such as impaired decision-making capacity.
  • Individuals with a history of a thrombotic event (DVT, PE, stroke, MI) or genetic disorder that increases risk of thrombosis
  • Participants undergoing unilateral facial filler (HA) injection
  • Participants with history of hypersensitivity to TXA or any of the other ingredients
  • Participants that are on current therapeutic anticoagulation therapy and aspirin use
  • Participants with stage 2 or greater renal failure
  • Participants on hemodialysis or peritoneal dialysis
  • History of diabetes or seizures
  • Current tobacco smokers
  • Acquired defective color vision

Recruiting US locations

  • University of Wisconsin - Madison

    Madison, WI 53705

    Site contact: Daniel Cho, MD, PhD · 608-263-7502 · chod@surgery.wisc.edu

Study contacts (from the official record)

  • Daniel Cho, MD, PhD · 608-263-6330 · chod@surgery.wisc.edu
All healthy volunteers studies in Wisconsin →
Effect of TXA on Reducing Bruising After Filler Injection (NCT06665594) | Bored Studies