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RecruitingAccepts healthy volunteersPhase 2

Effectiveness of Aquamin® in Mitigating Halitosis

University of Michigan · NCT05058638

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–99 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 2
Target enrollment
25
US sites recruiting
1
Study start
August 15, 2022
Record last updated
August 28, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to assess whether Aquamin®, a multi-mineral natural product from red marine algae, can help reduce halitosis when taken for 90 days.

Being studied: Aquamin

Conditions: Healthy; Halitosis

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Must be able to give written informed consent
  • Willing to follow study procedures of no eating, drinking, toothbrushing, smoking or using mouth rinse 60 minutes before study visits
  • Have stable oral health
  • Self-reported halitosis
  • A negative pregnancy test for pre-menopausal women with intact female reproductive organs, and the subject must agree to use appropriate birth control over the study period.

Exclusion Criteria

  • Pregnant or lactating women
  • Participating in any other interventional trials using an investigational drug
  • Diagnosed with any stomach or intestinal bleeding disorders (gastrointestinal bleeding from gastric or duodenal ulcers, or gastrin-secreting tumors) or active gastric/duodenal ulcers - peptic ulcer disease (in last 3 months) or with severe symptoms of ulcerative colitis or Crohn's disease
  • Any gastrointestinal or colonic malignancy; kidney disease, including kidney "stones" or hypercalcemia
  • Coagulopathy/hereditary hemorrhagic disorders/or receiving therapeutic doses of Coumadin or heparin
  • Have any severe oral condition that, in the opinion of the oral healthcare provide might impact the results of the study if the condition is treated
  • Have been treated for oral cancer within the past year
  • Taking any of the following within 30 days (will be eligible after completing 30 days of washout period):

Calcium; Vitamin D, including multivitamins that have low amounts of calcium/Vitamin D supplements; Oral steroids; Non-steroidal anti-inflammatory medications (NSAIDS); Antibiotics.

Recruiting US locations

  • University of Michigan School of Dentistry

    Ann Arbor, MI 48109

    Site contact: Iwonka Eagle · 734-615-8507 · ilenda@umich.edu

Study contacts (from the official record)

  • Muhammad N Aslam · 734-936-1897 · mnaslam@umich.edu
Effectiveness of Aquamin® in Mitigating Halitosis (NCT05058638) | Bored Studies