Effectiveness of Aquamin® in Mitigating Halitosis
University of Michigan · NCT05058638
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–99 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Phase 2
- Target enrollment
- 25
- US sites recruiting
- 1
- Study start
- August 15, 2022
- Record last updated
- August 28, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The purpose of this study is to assess whether Aquamin®, a multi-mineral natural product from red marine algae, can help reduce halitosis when taken for 90 days.
Being studied: Aquamin
Conditions: Healthy; Halitosis
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Must be able to give written informed consent
- Willing to follow study procedures of no eating, drinking, toothbrushing, smoking or using mouth rinse 60 minutes before study visits
- Have stable oral health
- Self-reported halitosis
- A negative pregnancy test for pre-menopausal women with intact female reproductive organs, and the subject must agree to use appropriate birth control over the study period.
Exclusion Criteria
- Pregnant or lactating women
- Participating in any other interventional trials using an investigational drug
- Diagnosed with any stomach or intestinal bleeding disorders (gastrointestinal bleeding from gastric or duodenal ulcers, or gastrin-secreting tumors) or active gastric/duodenal ulcers - peptic ulcer disease (in last 3 months) or with severe symptoms of ulcerative colitis or Crohn's disease
- Any gastrointestinal or colonic malignancy; kidney disease, including kidney "stones" or hypercalcemia
- Coagulopathy/hereditary hemorrhagic disorders/or receiving therapeutic doses of Coumadin or heparin
- Have any severe oral condition that, in the opinion of the oral healthcare provide might impact the results of the study if the condition is treated
- Have been treated for oral cancer within the past year
- Taking any of the following within 30 days (will be eligible after completing 30 days of washout period):
Calcium; Vitamin D, including multivitamins that have low amounts of calcium/Vitamin D supplements; Oral steroids; Non-steroidal anti-inflammatory medications (NSAIDS); Antibiotics.
Recruiting US locations
University of Michigan School of Dentistry
Ann Arbor, MI 48109
Site contact: Iwonka Eagle · 734-615-8507 · ilenda@umich.edu
Study contacts (from the official record)
- Muhammad N Aslam · 734-936-1897 · mnaslam@umich.edu
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