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Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness

University of Minnesota · NCT07219498

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–30 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
24
US sites recruiting
1
Study start
February 5, 2026
Record last updated
May 4, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to evaluate how probiotic supplementation (PS) influences post-exercise recovery in healthy, physically active young adults. Researchers aim to determine if the Lactobacillus casei probiotic strain reduces symptoms of delayed onset muscle soreness (DOMS) based on perceived muscle soreness, pressure pain threshold, and power output following exercise induced muscle damage (EIMD).

Being studied: Lactobacillus casei; Placebo Capsule(s)

Conditions: Exercise Induced Muscle Damage; Delayed Onset Muscle Soreness (DOMS)

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • complete a minimum of 150 minutes a week of at least moderate intensity exercise in either an endurance-based or resistance-based training style based on a self-reported physical activity over the past month
  • good general health with no injuries or health conditions that would affect physical activity
  • willing to abstain from consistent NSAID use and other probiotic supplements over the course of this study

Exclusion Criteria

  • known musculoskeletal injuries or physical limitations that could interfere with performing the designated physical activity required
  • underlying conditions that could place them at an increased risk during exercise such as cardiovascular, respiratory, or metabolic diseases
  • currently take a probiotic supplement, are prescribed and taking an antibiotic during the intervention, or report using NSAIDs or steroids within the recovery time window
  • report using an NSAID more than twice a week on a regular basis

Recruiting US locations

  • University of Minnesota

    Minneapolis, MN 55455

    Site contact: Jakob Fischer · 507-236-8051 · fisc0887@d.umn.edu

Study contacts (from the official record)

  • Jakob Fischer · 507-236-8051 · fisc0887@d.umn.edu
All nutrition & metabolism studies in Minnesota →
Effects of a 5-Week Probiotic Supplementation Intervention on… (NCT07219498) | Bored Studies