Effects of a Specific Substance in Smokers
Oregon Health and Science University · with National Institute on Drug Abuse (NIDA) · NCT04281979
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 21–40 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 60
- US sites recruiting
- 1
- Study start
- February 25, 2020
- Record last updated
- July 28, 2025
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
Although rates of cigarette use are declining, the proportion of nondaily smokers is rising, particularly among young adults. Among young adults, nondaily smoking is associated with negative health consequences and, for some, may lead to the establishment of life-long smoking patterns. The goal of this project is to understand the behavioral, psychological and neurobiological factors that contribute to cigarette use in nondaily smokers to aid the development of tailored evidence-based interventions.
Being studied: Study Agent; Placebo
Conditions: Smoking
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Participants must be 21-40 years old
- Right-handed
- Fluent in English
- Report smoking cigarettes or e-cigarettes 1-27 days in the past month
- Report binge drinking based on NIAAA criteria (5 or more drinks per occasion for males, 4 or more drinks per occasion for females) at least 1 time in the past 90 days without adverse incident
Exclusion Criteria
- Seeking treatment for substance use (e.g. nicotine or alcohol use)
- Moderate or Severe Nicotine Dependence
- Current alcohol use disorder
- Illicit substance use other than marijuana use in the past year
- Marijuana use more than 10 times in the past year
- Major neurological or medical illness - Significant head trauma - Current use of medication affecting the central nervous system
- MRI contraindications (e.g. irremovable metal on the body or pregnancy)
Recruiting US locations
Oregon Health and Science University
Portland, OR 97239
Site contact: Angelica M Morales, PhD · 8186794828 · ammorales@gmail.com
Study contacts (from the official record)
- Angelica M Morales, PhD · 503-494-4221 · moralean@ohsu.edu