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Effects of E-cigarette Use on Health

University of Wisconsin, Madison · with National Heart, Lung, and Blood Institute (NHLBI) · NCT06610838

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 21+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
600
US sites recruiting
1
Study start
January 6, 2025
Record last updated
December 24, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Electronic nicotine delivery systems (ENDS) are used by millions of Americans, however their long-term health effects are unknown. This research proposal will quantify the effects of long-term ENDS use on validated and novel biomarkers of cardiovascular and pulmonary disease and how they are influenced by use heaviness, age, body weight, and co-use of other products. This study will produce the most informative evidence to date on how long-term ENDS use affects cardiovascular and pulmonary health.

Being studied: Health Assessments

Conditions: Electronic Cigarette Use

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • greater than or equal to 21 years of age
  • has vaped a nicotine e-cigarette product at least 2 days/week for most weeks for greater than or equal to 12 months
  • plans to remain in catchment area for greater than or equal to 3 years
  • smoked 5 or fewer tobacco cigarettes in the past 6 months
  • no serious CV, pulmonary, or other medical problems
  • not currently pregnant
  • no plans to stop vaping

Exclusion Criteria

  • serious CV, pulmonary, or other medical problems (e.g., moderate or severe aortic stenosis, class III or IV heart failure, blood pressure greater than or equal to 160/100 mmHg, interstitial lung disease, sarcoidosis, Stage 3 or 4 cancer)
  • combusted or vaped cannabis use 3 days/week or more in the past 3 months
  • currently pregnant
  • not able to read an write English
  • incarceration

Recruiting US locations

  • UW Center for Tobacco Research and Intervention

    Madison, WI 53711

Study contacts (from the official record)

  • James Stein, MD · 608-262-2075 · jhs@medicine.wisc.edu
  • Timothy Baker, PhD · 503-387-5167 · tbb@ctri.wisc.edu
All smoking & vaping studies in Wisconsin →
Effects of E-cigarette Use on Health (NCT06610838) | Bored Studies