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EsophaCap for the Detection of Early Esophageal Carcinoma

Johns Hopkins University · with National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · NCT04214119

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
2500
US sites recruiting
2
Study start
January 12, 2016
Record last updated
December 16, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carcinoma), and gastric cancer via sponge cytology.

Conditions: Barrett Esophagus; Esophageal Cancer; Gastric Cancer

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Undergoing esophagogastroduodenoscopy at Johns Hopkins Hospital from 1/2016 to 12/2025
  • Age greater than 18 years
  • Patients must be able to swallow a capsule

Exclusion Criteria

  • Patients in either arm with extra-esophageal malignancies including head and neck and gastric cancer
  • Patients who have undergone esophagectomy
  • Patients who have undergone radiation to the chest
  • Patients who are younger than 18
  • Patients with esophageal stents
  • Patients with esophageal strictures disabling passage of the capsule

Recruiting US locations

  • Bayview Medical Center

    Baltimore, MD 21205

    Site contact: Stephen J Meltzer, M.D. · 410-502-6071 · smeltzer@jhmi.edu

  • Johns Hopkins Hospital

    Baltimore, MD 21205

    Site contact: Stephen Meltzer, M.D. · 410-502-6071 · smeltzer@jhmi.edu

Study contacts (from the official record)

  • Stephen J Meltzer, M.D. · 4105026071 · smeltzer@jhmi.edu
All healthy volunteers studies in Maryland →
EsophaCap for the Detection of Early Esophageal Carcinoma (NCT04214119) | Bored Studies