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RecruitingAccepts healthy volunteersPhase 1

Evaluate the Effect of Vimseltinib on P-glycoprotein (P-gp) Inhibition in Healthy Male Participants

Deciphera Pharmaceuticals, LLC · NCT07744802

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–55 · Men only
Healthy volunteers
Accepted
Study type
Interventional · Phase 1
Target enrollment
20
US sites recruiting
1
Study start
September 2026
Record last updated
September 25, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The main purpose of this study is to determine the effect of vimseltinib on pharmacokinetics of P-glycoprotein (P-gp) substrate (dabigatran) in healthy male participants. This study will last approximately 21 days.

Being studied: Vimseltinib; Dabigatran

Conditions: Healthy Male Participants

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Participants are in good general health, as required by the protocol and as determined by Principal Investigator.
  • Body mass index (BMI) from greater than or equal to (≥) 18 to less than or equal to ≤ 32 kilogram per square meter (kg/m\^2).
  • Adequate organ function and blood and urine tests, as required by the protocol and as determined by Principal Investigator.

Exclusion Criteria

  • History or presence of clinically significant diseases of the neurological, dermatological, renal, hepatic, gastrointestinal, cardiovascular, or musculoskeletal systems or history or presence of clinically significant psychiatric, immunological, endocrine, or metabolic disease as determined by Principal Investigator.
  • Unwilling or unable to comply with the requirements of the protocol.
  • Determined by Principal Investigator to be unsuitable to participate in the study for any other reason.

Recruiting US locations

Study contacts (from the official record)

  • Clinical Team · 888-724-3274 · clinicaltrials@deciphera.com
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Evaluate the Effect of Vimseltinib on P-glycoprotein (P-gp)… (NCT07744802) | Bored Studies