Skip to content
Bored Studies
RecruitingAccepts healthy volunteersEarly Phase 1

Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail Approach

Washington State University · with Office of Dietary Supplements (ODS), National Center for Complementary and Integrative Health (NCCIH) · NCT06693960

View Study & Apply (opens in a new tab)

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–64 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Early Phase 1
Target enrollment
16
US sites recruiting
1
Study start
September 26, 2024
Record last updated
June 4, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this clinical trial is to determine how the supplement oregano affects how the body metabolizes pharmaceutical drugs.

Being studied: Oregano; Drug cocktail

Conditions: Interaction

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Between 18-64 years old and healthy
  • Not taking any medications (prescription and non-prescription) or dietary/herbal supplements that can interfere with study drug pharmacokinetics
  • Willing to abstain from consuming dietary/herbal supplements and citrus juices for several weeks
  • Willing to abstain from cannabis/marijuana, hemp, and THC- and CBD-containing products for several weeks
  • Willing to abstain from consuming caffeinated beverages or other caffeine-containing products the evening before and the morning of the first day of each study arm
  • Willing to abstain from consuming any alcoholic beverages for at least 1 day prior to any study day and during the study day
  • Willing to use a secondary method of birth control that does not include the introduction or discontinuance of hormonal-based birth control (such as abstinence, copper IUD, or condoms). Specifically, regardless of the use hormonal-based birth control, a non-hormonal method should be used for the duration of the study and for three weeks following cessation of participation.
  • Willing to abstain from consuming oregano (as a food additive or otherwise) for the duration of the study
  • Geographically located within a 40-mile radius of Spokane and have the time to participate

Exclusion Criteria

  • Under 18 or over 64 years old
  • Taking medications or dietary/herbal supplements that can interfere with study drug pharmacokinetics
  • Have a major illness
  • Taking medication/supplements for a mineral deficiency
  • History of intolerance or allergy to oregano or any of the cocktail drugs (caffeine, dextromethorphan, losartan, midazolam, and omeprazole)
  • Use of cannabis/marijuana, hemp, and CBD- and/or THC-containing products within the last month
  • Currently using drugs or illicit substances for recreational purposes
  • Pregnant or nursing
  • Geographically located outside the 40-mile radius of Spokane and do not have the time to participate
  • Cannot read and speak English

Recruiting US locations

  • Washington State University College of Pharmacy and Pharmaceutical Sciences

    Spokane, WA 99202

    Site contact: Mary F Paine, RPh, PhD · 509-358-7759 · mary.paine@wsu.edu

Study contacts (from the official record)

  • Mary F Paine, RPh, PhD · 509-358-7759 · mary.paine@wsu.edu
All healthy volunteers studies in Washington →
Evaluating the Pharmacokinetics of Oregano and Potential… (NCT06693960) | Bored Studies