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Fasted vs. Fed State Exercise

Arkansas Colleges of Health Education · NCT07487090

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–59 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 2
Target enrollment
40
US sites recruiting
1
Study start
January 5, 2026
Record last updated
March 23, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Although many medications exist for both heart disease and obesity, cost, lack of access for all people, side effects and the desire for a more natural solution have left many people seeking lifestyle treatments such as exercise. Scientists know that exercise is highly beneficial for heart health. When exercise also produces weight loss, these benefits are much improved. Although using exercise to treat or prevent heart disease / obesity is recommended, not all people respond well. Some see significant weight loss and health improvements while others see little changes. For these reasons, new strategies surrounding the use and design of an exercise program are needed. One such strategy could be performing aerobic exercise before breakfast (fasted exercise). When exercising fasted, food/energy stores are low, and one relies on stored body fat for energy. This may help heart health and weight loss. This has never been tested in a program long enough to see such changes. This study will, for the first time, assess the effects of a 16-week aerobic exercise program performed fasted compared to after eating. Outcomes will include blood fats, blood pressure, fat-burning abilities and weight loss.

Starting an exercise program can also make people to eat more. This limits the success of exercise. The study will also evaluate ways fasted exercise could change eating, as it possible that fasted exercise could also cause people to eat more, which would limit weight loss and health improvements.

Being studied: 16 week exercise intervention

Conditions: Obesity; Exercise; Weight Loss

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Aged 18-59
  • BMI 25-45
  • Healthy enough to exercise

Exclusion Criteria

  • Taking medications or supplements that are known to influence energy expenditure,
  • Currently exercising more than once per week
  • Currently dieting for weight loss
  • Currently taking weight loss drugs
  • Have had a previous weight loss surgery
  • Currently diagnosed with Diabetes
  • Currently diagnosed with heart disease (Heart failure, uncontrolled hypertension, uncontrolled hypercholesterolemia, Coronary heart disease)

Recruiting US locations

  • Arkansas Colleges of Health Education Research Institure Health and Wellness Center

    Fort Smith, AR 72916

    Site contact: Kyle D Flack, PhD · (479) 434-4019 · kyle.flack@achehealth.edu

Study contacts (from the official record)

  • Kyle D Flack, PhD · (479) 434-4019 · kyle.flack@achehealth.edu
  • Blake Metcalf, DCN · 479-434-4003 · blake.metcalf@achehealth.edu
All weight loss studies in Arkansas →
Fasted vs. Fed State Exercise (NCT07487090) | Bored Studies