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FDG PET/MR Imaging of Peripheral Pain Generators

University of Wisconsin, Madison · with National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Arthroscopy Association of North America · NCT06171659

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–85 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
128
US sites recruiting
1
Study start
November 19, 2024
Record last updated
July 17, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this research is to determine if a PET/MRI scan using FDG can accurately identify the source of chronic pain. Identifying the source of pain may help doctors treat chronic pain more effectively. Approximately 128 participants will be enrolled and can expect to be on study for up to 12 months.

Being studied: FDG radiotracer; PET/MRI; PET/CT imaging

Conditions: Pain; Nociceptive Pain

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria: Persistent Post-Surgical Pain Patients

  • 18-85 years old
  • Presents with persistent pain with pain score of ≥4 on Numerical Rating Scale [0:10] for at least 6 months following joint arthroplasty or arthroscopy.
  • Able and willing to provide informed consent
  • Willing and able to undergo PET/MRI (arthroplasty and arthroscopy participants) and PET/CT (arthroplasty participants only)

Inclusion Criteria: Asymptomatic controls

  • 18-85 years old
  • Asymptomatic (pain score of ≤2 on the NRS) for at least 6 months following joint arthroplasty or arthroscopy.
  • Able and willing to provide informed consent
  • Willing and able to undergo PET/MRI

Exclusion Criteria

  • Inability to understand and communicate with the investigators to complete the study-related questionnaires.
  • Any co-morbidity which results in severe systemic disease limiting function as defined by the American Society of Anesthesiology (ASA) physical status classification > 3, such as the presence of current or past (6 months) pulmonary, hepatic, renal disease, arthritis, hematopoietic, and neurological diseases not related to chronic pain.
  • Pregnant or breastfeeding. (Individuals with childbearing potential will be asked to verbally confirm they are not pregnant. If they cannot confirm, they will have a urine pregnancy test either at the imaging study visit or within 7 days prior to the imaging study visit.)
  • Subject with contraindication(s) to or inability to undergo PET/MRI
  • Current diagnosis of malignancy of any kind. Participants in remission for at least two years and not undergoing any treatment may be considered per investigator discretion
  • Current enrollment in a scientific interventional or treatment study.
  • Subject unable or unwilling to provide informed consent

Recruiting US locations

  • UW School of Medicine and Public Health

    Madison, WI 53792

Study contacts (from the official record)

  • Radiology Studies · 608-282-8349 · Radstudy@uwhealth.org
All healthy volunteers studies in Wisconsin →
FDG PET/MR Imaging of Peripheral Pain Generators (NCT06171659) | Bored Studies