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RecruitingAccepts healthy volunteersEarly Phase 1

Gene Expression Changes In Young and Geriatric Skin

Wright State University · NCT03932162

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 21+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Early Phase 1
Target enrollment
24
US sites recruiting
1
Study start
September 6, 2019
Record last updated
February 6, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study does not involve any particular diagnosis. The goal of this research study is to explore the effects of artificial sunlight (ultraviolet B radiation; UVB) on the skin of young adults versus geriatric adults. Sunlight exerts many effects on the body. There is evidence that in response to ultraviolet B radiation (UVB), which are the burning rays of sunlight, young adult skin responds differently than geriatric skin. In fact, researchers feel that this difference in how the skin reacts to UVB is why skin cancers are found in older skin. Researchers believe that a major difference between young adult and geriatric skin is that young skin has a lot of a protein called insulin-like growth factor-1 (IGF-1), whereas geriatric skin has very little. The current study will test how young adult versus geriatric skin responds to UVB, and if geriatric skin treated with an injection of small amount of IGF-1 drug will then act like young skin.

Being studied: Insulin-Like Growth Factor 1; No Insulin-Lie Growth Factor 1

Conditions: UVB Phototherapy Burn; Insulin-like Growth Factor 1; Aging

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Male/Female
  • White skin (Fitzpatrick types I and II)
  • Age 21-30 or 65 and older
  • Able to comprehend procedures/risks

Exclusion Criteria

  • Known photosensitivity
  • Currently on photosensitizing medications
  • Diabetes Mellitus
  • History of abnormal scarring
  • History of skin infections
  • Known allergy to lidocaine local anesthetic
  • Pregnancy or nursing
  • Other serious health issues

Recruiting US locations

Study contacts (from the official record)

  • Manager, Clinical Research Operations · 937-245-7500 · pturesearch@wrightstatephysicians.org
  • Regulatory Specialist · 937-245-7500 · pturesearch@wrightstatephysicians.org
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Gene Expression Changes In Young and Geriatric Skin (NCT03932162) | Bored Studies