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Genes and Environment in Multiple Sclerosis

Columbia University · with University of Pittsburgh, Brigham and Women's Hospital · NCT01353547

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
5000
US sites recruiting
3
Study start
October 1, 2017
Record last updated
May 14, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of the research study is to identify the genetic, environmental and immune profiles that may increase a person's risk of developing multiple sclerosis (MS). While MS is not a disease caused by a single variation in genetic material (DNA), a single environmental factor, or a single malfunction in immune cells, there are genetic alterations, environmental exposures and immunologic factors that make the development of MS more likely. Obtaining information about who is at risk for MS will be beneficial in the future if the investigators can identify effective ways to prevent or slow down the progression of this disease.

Conditions: Multiple Sclerosis

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • First Degree Relatives of Patients with MS, or
  • Patients who have received anti-TNFa therapy as treatment for inflammatory diseases other than MS such as Crohn's disease, psoriasis and rheumatoid arthritis, or
  • Patients that have been referred for an evaluation of first presentation of neurologic symptoms but do not have a diagnosis of MS
  • Live in the United States

Exclusion Criteria

  • Does not match any of the inclusion criteria

Recruiting US locations

  • National Institute of Neurological Disorders and Stroke

    Bethesda, MD 15213

    Site contact: Daniel S Reich, MD, PhD

  • Columbia University Irving Center

    New York, NY 10032

    Site contact: Juliana Oyegunle · 212-305-2434 · jbo2120@cumc.columbia.edu

  • University of Pittsburgh

    Pittsburgh, PA 15213

    Site contact: Zongqi Xia, MD, PhD

Study contacts (from the official record)

  • Juliana Oyegunle · 212-305-2434 · jbo2120@cumc.columbia.edu
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Genes and Environment in Multiple Sclerosis (NCT01353547) | Bored Studies