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Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

National Heart, Lung, and Blood Institute (NHLBI) · NCT04014348

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 19–45 · Women only
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
250
US sites recruiting
1
Study start
October 20, 2021
Record last updated
October 26, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Background

Heart disease is a leading cause of death in the United States. Healthy diet and exercise improve heart health. Some features of where a person lives can lead to stress and decrease chances for exercise. Researchers want to see how these factors may increase the risk of heart disease in women.

Objective

To see if there are differences in stress levels between women who live in different parts of Washington, DC. Also, to see how these women use their neighborhoods for exercise.

Eligibility

Healthy white or black females ages 19-45 who live in Washington, DC, who have access to a smartphone

Design

Participants may stay at the NIH Clinical Center overnight for a 2-day visit.

Visit 1 will include:

Physical exam

Blood tests

Electrocardiogram: Electrodes on the participant s skin will measure heart activity.

PET/CT scan: Participants will get an injection. They will lie in a machine that takes pictures of the body.

Surveys

Body size measurements

Nutrition consultation

Blood vessel tests: This is measured with blood pressure cuffs, a device placed on the participant s fingertip, and a probe placed on the participant s neck.

Resting Energy Expenditure: Participants will breathe under a clear hood for 45 minutes.

Participants will be followed for about 2 weeks. They will wear a device on the wrist and carry a GPS device. Through a mobile app, they will answer short daily surveys on stress and exercise.

Visit 2-

Device return

Nutritional consultation

...

Conditions: Cardiovascular (CV) Risk

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria
  • INCLUSION CRITERIA:

Individuals eligible for this protocol

  • A healthy self-identified White female (i.e. self-identifies as White or of European descent) or healthy Black female (i.e. self-identifies as Black, African American, or of African descent)
  • Must be between 19 to 45 years of age
  • Must not have any chronic health condition (i.e.: cardiovascular, autoimmune, endocrinologic), or active infection
  • Must be living in Washington, DC
  • Must have access to a smartphone
  • Must be able to provide informed consent
  • Must speak English.

EXCLUSION CRITERIA

  • Pregnant or breast feeding
  • Physically unable to perform physical activity for any reason
  • Subject had weight changes greater than 20% over the past 3 months
  • Subject is obese by our measurements (BMI greater than or equal to 35.0 kg/m\^2)
  • If you have high or low blood pressure requiring medications
  • Diabetes
  • History of severe mental illnesses, treated with hospitalization
  • If you have evidence of active thyroid disease requiring medications
  • If you are taking medication for chronic non-mental health related illness (ie: cardiovascular, autoimmune, endocrinologic)
  • If you have food allergies or highly restrictive diets that may prevent your ability to consume a controlled metabolic diet.
  • If you are a current smoker (tobacco products)

Recruiting US locations

  • National Institutes of Health Clinical Center

    Bethesda, MD 20892

    Site contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) · 800-411-1222 · prpl@cc.nih.gov

Study contacts (from the official record)

  • Marie Marah, R.N. · (301) 640-1701 · marie.marah@nih.gov
  • Tiffany M Powell-Wiley, M.D. · (301) 496-5817 · powelltm2@mail.nih.gov
All heart & blood pressure studies in Maryland →
Geospatial Analysis of Neighborhood Environmental Stress in… (NCT04014348) | Bored Studies