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Handgrip Training and Brain Blood Flow Regulation

Florida State University · NCT07223645

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Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–35 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
40
US sites recruiting
1
Study start
October 27, 2025
Record last updated
October 7, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study aims to investigate the effect of isometric handgrip training on brain blood vessel function in physically inactive adults. Isometric handgrip training is a promising strategy for lowering blood pressure and improving vascular health, but no previous investigations have studied the effect of training on markers of brain blood vessel function. Based on previous work showing improvements in vascular function after isometric handgrip training, we hypothesize that isometric handgrip training will improve key markers of cerebrovascular function.

Being studied: Handgrip Training

Conditions: Inactivity/Low Levels of Exercise

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • 18 to 35 years old
  • Body mass index ≤30 kg/m2 (without obesity)
  • Physically inactive (not meeting the current recommendations of ≥150 minutes per week of moderate-to-vigorous aerobic exercise and not ≥2 days per week of resistance training) in last 6 months
  • Have a smartphone and are willing to download mobile applications used in this project

Exclusion Criteria

  • Having an overt chronic condition (e.g., cardiovascular, cerebrovascular, etc.)
  • Being pregnant, planning to become pregnant, or breastfeeding/lactating
  • Regular use of nicotine products in the past 6 months
  • Recent head injury/trauma or concussion

Recruiting US locations

  • Florida State University

    Tallahassee, FL 32306

    Site contact: Joseph Watso, PhD · 850-644-5260 · jwatso@fsu.edu

Handgrip Training and Brain Blood Flow Regulation (NCT07223645) | Bored Studies