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Human Intracranial Electrophysiology

Dartmouth-Hitchcock Medical Center · with Dartmouth College · NCT05529264

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
175
US sites recruiting
1
Study start
January 17, 2023
Record last updated
January 15, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study will enroll patients with epilepsy who are being evaluated for epilepsy surgery and have electrodes implanted in the brain and/or have electrodes on the scalp. Additionally, this study will recruit normal and online controls (participants who do not have epilepsy). Participants will be asked to participate in 1 to 2 (30-90 minutes) daily sessions designed to test aspects of human cognition such as memory, speech, language, feeling, movement, attention, sound perception, and emotions. Generally, this will involve working on a computer, looking at pictures or watching videos, and answering questions. Additionally, participants may be asked to be hooked up to additional equipment such as eye tracker, electrical stimulator, heart rate monitor, sweat monitor or other non-invasive equipment. The overall aim of this study is to use human intracranial electrophysiology (the recording of the electrical activity of the human brain) to study localization and function of the human brain.

Being studied: Memory Tasks; Attention/arousal tasks; Language tasks; Visuospatial tasks; Auditory Tasks; Brain Stimulation; Social Emotional Task; Recording of facial expressions; Judgement/Impulsivity Task

Conditions: Epilepsy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Patients with Intracranial EEG: Inclusion Criteria

  • Patients must be age 18 years or older. There is no upper age limit.
  • Patients must have a diagnosis of refractory epilepsy undergoing intracranial EEG recording for clinical purposes.

Patients with Intracranial EEG: Exclusion Criteria

  • Patient has additional neurological condition (such as stroke or dementia) or a psychiatric condition (such as active psychosis or suicidal ideation) and are deemed inappropriate for the study
  • Patients are not able to provide informed consent for any reason (e.g. encephalopathic, experiencing a seizure)

Patients with Scalp EEG: Inclusion Criteria

  • Patients must be age 18 years or older. There is no upper age limit.
  • Patients must have a probable diagnosis of epilepsy.

Patients with Scalp EEG: Exclusion Criteria

  • Patient has additional neurological condition (such as stroke or dementia) or a psychiatric condition (such as active psychosis or suicidal ideation) and are deemed inappropriate for the study
  • Patients are not able to provide informed consent for any reason (e.g. encephalopathic, experiencing a seizure)

Normal Controls: Inclusion Criteria

  • Participants must be age 18 years or older. There is no upper age limit.
  • Participants must be able to provide informed consent for themselves.

Normal Controls: Exclusion Criteria

  • Determined not to be appropriate normal control for the study population

Recruiting US locations

  • Dartmouth-Hitchcock Medical Center

    Lebanon, NH 03776

    Site contact: Krzysztof A Bujarski, MD · 603 650-5104 · krzysztof.a.bujarski@hitchcock.org

Study contacts (from the official record)

  • Krzysztof A Bujarski, MD · 603-650-5104 · krzysztof.a.bujarski@hitchcock.org
  • Gina Kersey · (603) 650-0260 · Gina.E.Kersey@Hitchcock.ORG
All neurology studies in New Hampshire →
Human Intracranial Electrophysiology (NCT05529264) | Bored Studies